Recombinant Mouse Nicotinamide riboside kinase 1 (Nmrk1)

中文名稱：

小鼠Nmrk1重組蛋白
貨號：

CSB-YP835569MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Nmrk1重組蛋白
貨號：

CSB-EP835569MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nmrk1重組蛋白
貨號：

CSB-BP835569MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nmrk1重組蛋白
貨號：

CSB-MP835569MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nmrk1
Uniprot No.：

Q91W63
別名：

Nmrk1; Nrk1; Nicotinamide riboside kinase 1; NRK 1; NmR-K 1; EC 2.7.1.22; Nicotinic acid riboside kinase 1; EC 2.7.1.173; Ribosylnicotinamide kinase 1; RNK 1; Ribosylnicotinic acid kinase 1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區(qū)域：

1-195
氨基酸序列

MKRFVIGIGG VTNGGKTTLA KSLQKHLPNC SVISQDDFFK PESEIDIDEN GFLQYDVLEA LNMEKMMSAV SCWMENPGSS AGPAALESAQ GVPILIIEGF LLFNYKPLDT IWNRSYFLTV PYEECKRRRS TRVYEPPDPP GYFDGHVWPM YLKHRQEMSS ITWDIVYLDG TRSEEDLFSQ VYEDVKQELE KQNGL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN).
基因功能參考文獻：
1. NRK1 KO myotubes revealed redundancy in the NRK1/2 dependent metabolism of nicotinamide riboside to NAD+. PMID: 28752046
2. adenoviral delivery of NRK1 in diet- and age-induced mice elevates hepatic NAD(+) levels, reduces hepatic steatosis, and improves glucose tolerance and insulin sensitivity. PMID: 29678570
3. nicotinamide riboside kinase 1 (NRK1) is necessary and rate-limiting for the use of exogenous nicotinamide riboside and nicotinamide mononucleotide for NAD(+) synthesis. PMID: 27725675
蛋白家族：

Uridine kinase family, NRK subfamily
數(shù)據(jù)庫鏈接：

KEGG: mmu:225994

STRING: 10090.ENSMUSP00000037198

UniGene: Mm.211595