Recombinant Mouse Nexilin (Nexn)

中文名稱：

小鼠Nexn重組蛋白
貨號：

CSB-YP756025MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Nexn重組蛋白
貨號：

CSB-EP756025MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Nexn重組蛋白
貨號：

CSB-EP756025MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nexn重組蛋白
貨號：

CSB-BP756025MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nexn重組蛋白
貨號：

CSB-MP756025MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nexn
Uniprot No.：

Q7TPW1
別名：

Nexn; Nexilin; F-actin-binding protein
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-607
氨基酸序列

MNDVSQKAEI KEMLASDDEE ESSPKIEKAY VPKLTGTVKG KFDEMEKHRQ EEQRKRTEEE RKRRIEQDLL EKRKIQRELA KRAEQIEDIN NTGTESASEE GDDSLLITVV PAKSYKTPGK TKDPEDLDRE EGNGRTNHEE DKMRYEEECR VLKEAKCLSL VMDDETEAKK ESHFPGKLKS TFEELERQRQ ENRKKQAEEE ARRRLEEERR SFEEARRHMV NEEDENQDRE TVFKEYRPGK LKLSFEEIER QRREDEKRKA EEEARRRIEE EKAAFAEARR SMVLDDDSPE IYKTVSQESL TPGKLEINFE QLLRQKMEEE RRRTEEERRH KLEMEKQEFE QLRQEMGKEE EENESFGLSR EYEELIKLKR SGSIQAKNLK SKFEKIGQLS EKEVQKKIEE ERAKRRAIDL EIKEREAENF HEDDDVDVRP AKKSESPFTH KVNMKARFEQ MAKAREEEEQ RRIEEQKLLR MQFEQKEIDA ALQKKREDEE EEEGSIVNGS TTEDEEQTRS GAPWFKKPLR NTSVVDSEPV RFTVKVTGEP KPEITWWFEG EILQDGEDYQ YIERGETYCL YLPETFPEDG GEYMCKAVNN KGSAASTCIL TIEMDDY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity.
基因功能參考文獻：
1. these results further emphasize the role of NEXN in dilated cardiomyopathy and suggest a novel role in endomyocardial fibroelastosis. PMID: 26659360
2. NEXN as a novel gene for ASD and its function to inhibit GATA4 established a critical regulation of an F-actin binding protein on a transcription factor in cardiac development PMID: 24866383
亞細胞定位：

Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cytoplasm, myofibril, sarcomere, Z line.
數據庫鏈接：

KEGG: mmu:68810

STRING: 10090.ENSMUSP00000037120

UniGene: Mm.200188