Recombinant Mouse Neurexin-3-alpha (Nrxn3), partial

中文名稱：

小鼠Nrxn3重組蛋白
貨號：

CSB-YP761313MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Nrxn3重組蛋白
貨號：

CSB-EP761313MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Nrxn3重組蛋白
貨號：

CSB-EP761313MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nrxn3重組蛋白
貨號：

CSB-BP761313MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nrxn3重組蛋白
貨號：

CSB-MP761313MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nrxn3
Uniprot No.：

Q6P9K9
別名：

Nrxn3; Neurexin-3; Neurexin III-alpha; Neurexin-3-alpha
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.
基因功能參考文獻：
1. In the present study, we report that Nrxn3beta is processed by the metalloproteases ADAM10, ADAM17, and by the intramembrane-cleaving protease gamma-secretase, producing secreted neurexin3beta (sNrxn3beta) and a single intracellular domain (Nrxn3beta-ICD). Thea authors show that sNrxn3beta produced by the cells of the dentate gyrus increases the spine density of newborn neurons. PMID: 27991559
2. Nrxn3 is responsible for the neuroligins (NLs)-induced assembly of GABAergic synapses in co-culture. Importantly, lentivirus-based expression of Nrxn3 containing exon 20 restores the reduced NLs-induced GABAergic contacts in the SLM2 E/E co-culture. PMID: 28939043
3. Alternative splicing of presynaptic neurexin-3 controls postsynaptic AMPA receptor trafficking, revealing an unanticipated alternative splicing mechanism for trans-synaptic regulation of synaptic strength and long-term plasticity. PMID: 23827676
4. N-terminal sequencing of cow neurexin III beta provides evidence for signal peptide PMID: 8163501
5. N-terminal sequencing of rat neurexin III alpha provides evidence for signal peptide PMID: 9856994
6. NRXN3 adhesion molecules may play an important role in the synaptic plasticity of neurons involved in the indirect pathways of basal ganglia PMID: 18418251
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亞細胞定位：

Membrane; Single-pass type I membrane protein.
蛋白家族：

Neurexin family
組織特異性：

Brain and arteries (at protein level).
數據庫鏈接：

KEGG: mmu:18191

STRING: 10090.ENSMUSP00000129678

UniGene: Mm.425766