Recombinant Mouse N-terminal EF-hand calcium-binding protein 2 (Necab2)

中文名稱：

小鼠Necab2重組蛋白
貨號：

CSB-YP849694MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Necab2重組蛋白
貨號：

CSB-EP849694MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Necab2重組蛋白
貨號：

CSB-EP849694MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Necab2重組蛋白
貨號：

CSB-BP849694MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Necab2重組蛋白
貨號：

CSB-MP849694MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Necab2
Uniprot No.：

Q91ZP9
別名：

Necab2; Efcbp2; N-terminal EF-hand calcium-binding protein 2; EF-hand calcium-binding protein 2; Neuronal calcium-binding protein 2
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-389
氨基酸序列

MCERAARLCR AGAHRLLREP PPQGRALGGL LRWVGARMGE PRAPLVPDIP SADPGPGPAA SRGGTAVILD IFRRADKNDD GKLSLEEFQL FFADGVLNEK ELEGLFHTID SDNTNHVDTK ELCDYFVEHM GDYEDVLASL ETLNHSVLKA MGYTKKVYEG GSNVDQFVTR FLLKETANQI QSLLSSVESA VEAIEEQTSQ IRQDHCKPSH AVNESRYGGP TPPYIPNHKL VAPEPMKSLP VATGEPKEDG LEGQISRLAE LIGRLESKTL SFDLQQRLSD EEGTNMHLQL VRQEMAVCPE QLSEFLDSLR QYLRSTAEER NCFHVAAVRM ADGLTFVIYE FWETEEEWKR HLQSPVCKAF RHVKVDTLSQ PEALSQISVP AAWCTSGRD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.
基因功能參考文獻：
1. The genes for the three Necab's, including Necab-2, were expressed in specific, non-overlapping areas of the hippocampus. PMID: 23850650
亞細胞定位：

Cytoplasm. Cell projection, dendrite. Cell projection, axon. Cell membrane.
組織特異性：

Expressed in the iris, in the ciliary margin of the retina and in the inner portion of the neural retina. Expressed in the spinal dorsal horn with especially strong expression in lamina IIi; found in excitory synaptic boutons (at protein level).
數據庫鏈接：

KEGG: mmu:117148

UniGene: Mm.356184

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