Recombinant Mouse Myocardial zonula adherens protein (Myzap)

中文名稱：

小鼠Myzap重組蛋白
貨號(hào)：

CSB-YP659730MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Myzap重組蛋白
貨號(hào)：

CSB-EP659730MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Myzap重組蛋白
貨號(hào)：

CSB-EP659730MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Myzap重組蛋白
貨號(hào)：

CSB-BP659730MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Myzap重組蛋白
貨號(hào)：

CSB-MP659730MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Myzap
Uniprot No.：

Q3UIJ9
別名：

Myzap; Myozap; Myocardial zonula adherens protein
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達(dá)區(qū)域：

17-466
氨基酸序列

KSPG TPSRRANVCR LRLTVPPENP VPQQTEKKIE RKDQPPELSN GESTKRLPQG VVYGVVRRSD PNQQKEMVVY GWSTNQLKEE MNYIKDVRAT LEKVRKRMYG DYDEMRQKIR QLTQDLSVSH AQQDYLDSHI QAQASALDSF NAMNAALASD SVGLQKTLVD VTLENSHIKD QIRHLQQTYE ASMDKLREKQ RQLEAAQMEN QLLKMRVESS QEANAEVMRE MTRKLYSQYE EKLQEAQRKH SAEKEVLLEE TNSFLKAIEE ANKKMEAAEL SLEEKDQKIG ELDRLIERME KERHQLQLQL LEHETEMSGE MADSDKNRYQ QLEEASASLR ERIRHLDDMV HCQQKKVKQM VEEIESLKKK VQQKQLLILQ LLEKISFLEG ENNELQSRLD YLTETQPKTE VETREIGVGC DLLPSPTGRT REITMPSRSY TPYTRVLELS SKKTLT
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Plays a role in cellular signaling via Rho-related GTP-binding proteins and activation of transcription factor SRF. Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1.
基因功能參考文獻(xiàn)：
1. Cardiac overexpression of Myozap results in cardiomyopathy with hypertrophy and left ventricular dilation. PMID: 24698889
2. Reveal myozap as a previously unrecognized component of a Rho-dependent signaling pathway that links the intercalated disc to cardiac gene regulation. PMID: 20093627
亞細(xì)胞定位：

Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, Z line. Cell junction. Note=Detected predominantly at the intercalated disk in cardiomyocytes, and at low levels on sarcomeric Z disks. Colocalizes with F-actin. Colocalizes with cortical actin.
蛋白家族：

MYZAP family
組織特異性：

Detected in heart myocardium and lung.
數(shù)據(jù)庫鏈接：

KEGG: mmu:102371

STRING: 10090.ENSMUSP00000091342

UniGene: Mm.27585