Recombinant Mouse Mesoderm induction early response protein 1 (Mier1)

中文名稱：

小鼠Mier1重組蛋白
貨號：

CSB-YP713184MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Mier1重組蛋白
貨號：

CSB-EP713184MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Mier1重組蛋白
貨號：

CSB-EP713184MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Mier1重組蛋白
貨號：

CSB-BP713184MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Mier1重組蛋白
貨號：

CSB-MP713184MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mier1
Uniprot No.：

Q5UAK0
別名：

Mier1; Kiaa1610; Mesoderm induction early response protein 1; Early response 1; Er1; Mi-er1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-511
氨基酸序列

MAEPSVESSS PGGSATSEDH EFDPSADMLV HDFDDERTLE EEEMMEGETN FSSEIEDLAR EGDMPIHELL SLYGYDSTVR LPEEEEEEEE EEEGEDDEDA DNDDNSGCSG ENKEENIKDS SGQEDETQSS NDDPSQSVTS QDAQEIIRPR RCKYFDTNSE IEEESEEDED YIPSEDWKKE IMVGSMFQAE IPVGVCRYKE NEKVYENDDQ LLWDPECLPE EKVVVFLKDA SRRTGDEKGV EAIPEGSHIK DNEQALYELV KCSFDTEEAL RRLRFNVKAA REELSVWTEE ECRNFEQGLK AYGKDFHLIQ ANKVRTRSVG ECVAFYYMWK KSERYDFFAQ QTRFGKKKYN LHPGVTDYMD RLLDESESAA SSRAPSPPPT ASNSSNSQSE KEDGAVSSRN QNGVSSNGPG EILNKEEVKV EGLHVNGPTG GNKKPLLTDM DTNGYEANNL TTDPKLAHMT ARNENDFDEK NERPAKRRRI NSSGKESPGS SEFFQEAVSH GKFEEHENTN D
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing.
基因功能參考文獻：
1. Biochemical analysis of the BAHD1-associated multiprotein complex identifies MIER proteins as novel partners of BAHD1 and suggests that BAHD1-MIER interaction forms a hub for histone deacetylases and methyltransferases PMID: 26938916
2. characterization of the mouse ortholog of mi-er1 PMID: 16147882
3. This study represents the first immunohistochemical analysis of MI-ER1alpha expression in mammals. PMID: 17622490
亞細胞定位：

Nucleus.
組織特異性：

Ubiquitously expressed. Isoform 1 is only expressed in testis.
數據庫鏈接：

KEGG: mmu:71148

STRING: 10090.ENSMUSP00000030247

UniGene: Mm.288721