Recombinant Mouse Meiotic nuclear division protein 1 homolog (Mnd1)

中文名稱：

小鼠Mnd1重組蛋白
貨號：

CSB-YP818344MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Mnd1重組蛋白
貨號：

CSB-EP818344MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Mnd1重組蛋白
貨號：

CSB-EP818344MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Mnd1重組蛋白
貨號：

CSB-BP818344MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Mnd1重組蛋白
貨號：

CSB-MP818344MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mnd1
Uniprot No.：

Q8K396
別名：

Mnd1; Meiotic nuclear division protein 1 homolog
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-205
氨基酸序列

SKKRGLSGE EKRTRMMEIF FETKDVFQLK DLEKLAPKEK GITAMSVKEV LQSLVDDGMV DCERIGTSNY YWAFPSKALH ARKRKLEALN SQLSEGSQKH ADLQKSIEKA RVGRQETEER AMLAKELSSF RDQRQQLKAE VEKYRECDPQ VVEEIREANK VAKEAANRWT DNIFAIKSWA KRKFGFEESK IDKNFGIPED FDYID
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
基因功能參考文獻：
1. HOP2-MND1 enhances the interaction of RAD51 with nucleotide cofactors and modifies its DNA-binding specificity. PMID: 24943459
2. The Hop2-Mnd1 heterodimer efficiently condenses double-stranded DNA via formation of a bright spot or DNA condensate. PMID: 21112301
3. data reveal an interplay among Hop2, Mnd1 and Rad51 and Dmc1 in the formation of the first recombination intermediates during meiosis [Mnd1] PMID: 15834424
4. Hop2/Mnd1 greatly stimulates Dmc1 to promote synaptic complex formation on long duplex DNAs PMID: 17639081
5. Characterization of the MND1 gene in Saccharomyces cerevisiae and identification of a potential homolog in mouse. PMID: 11940665
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亞細胞定位：

Nucleus.
蛋白家族：

MND1 family
數據庫鏈接：

KEGG: mmu:76915

STRING: 10090.ENSMUSP00000048262

UniGene: Mm.274829