Recombinant Mouse MAGUK p55 subfamily member 4 (Mpp4)

中文名稱：

小鼠Mpp4重組蛋白
貨號：

CSB-YP761304MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Mpp4重組蛋白
貨號：

CSB-EP761304MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Mpp4重組蛋白
貨號：

CSB-EP761304MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Mpp4重組蛋白
貨號：

CSB-BP761304MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Mpp4重組蛋白
貨號：

CSB-MP761304MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mpp4
Uniprot No.：

Q6P7F1
別名：

Mpp4; Dlg6; MAGUK p55 subfamily member 4; Discs large homolog 6; mDLG6
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-635
氨基酸序列

MRQSDRGAEL TNEDRALPTP PDPENGLSGI LRLLLQELSL FYSRDVNGLC LLYDLLHSPW LQALLKVYDC LQRFKEKKLV PDTTHAQILA CEVLELLPKA SGSPEIQELR QVLQAPHCKA LLSAHDTVAQ KDFEPLLPPL PDNIPDSEEA MRIVCLVKNQ QPLGATIKRH EITGDILVAR VIHGGLVERS GLLYAGDKLV EVNGVSVEGL DPEQVIHILA MSCGTIMFKV IPVSAPPVSS QKMVYVRAMI DYWPQEDPDI PCMDAGLPFL KGDILQIVDQ NDALWWQARK ISDLTICAGL IPSNHLLKRK QREFWWSQPY QPHTCLKSTR ALSMEEEDSM KIDEKCVEAD EETFESEELA EAKDEFVGDG QKFFIAGFRR SMRLCRRKSH FSQLHASLCC SCSCYSAVGA PYEEVVRYQR QPADKHRLIV LVGPSGVGVN ELRRQLIGCN PSCFQSAVPH TTRFPKSYEM DGREYHYVSR ETFESLMYGH KMLEYGEYKG HLYGTSVNAV HAVLDEGKIC IMDLEPQDIQ SARTRDLKPY VIFIKPPNTS SMRHSRKNAK ITTDYYVDMK FKDEDLQEME ELAQKMESQF GQFFDHVIVN DNLQDACGQL LSAIQKAQEE LQWVPEAWVS PDTES
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May play a role in retinal photoreceptors development.
基因功能參考文獻：
1. Results describe the temporal and spatial expression patterns of mouse membrane palmitoylated protein 4 (Mpp4) gene. PMID: 12859944
2. Association of Veli3 with MPP4 suggests that the MAGUKs recruit Veli3 and its binding partners to different cellular regions of the retina where they may participate in the organization of specialized intercellular junctions. PMID: 15558731
3. These findings suggest that Mpp4 coordinates Psd95/Veli3 assembly and maintenance at synaptic membranes. Mpp4 is a critical recruitment factor to organize scaffolds at the photoreceptor synapse. PMID: 16520334
4. Results show that Mpp4 organizes a presynaptic protein complex and has a role in modulating Ca(2+) homeostasis and synaptic transmission in rod photoreceptors. PMID: 17341488
亞細胞定位：

Cytoplasm. Note=Localized at photoreceptor synaptic terminals in retina. Localized in rod and cone photoreceptors at the plasma membrane and at membranes of intracellular vesicles around the subapical region (SAR) and adherens junction, and in the outer plexiform layer (OPL).
蛋白家族：

MAGUK family
組織特異性：

Detected in the retina (at protein level). Highly enriched in the retina where it is mainly expressed by rod photoreceptors; detected in the inner segment of the photoreceptor layer and in the outer nuclear layer. Also detected at much lower levels in pin
數據庫鏈接：

KEGG: mmu:227157

STRING: 10090.ENSMUSP00000109914

UniGene: Mm.474049