Recombinant Mouse Lysine--tRNA ligase (Kars)

中文名稱(chēng)：

小鼠Kars重組蛋白
貨號(hào)：

CSB-YP858769MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

小鼠Kars重組蛋白
貨號(hào)：

CSB-EP858769MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

小鼠Kars重組蛋白
貨號(hào)：

CSB-EP858769MO-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

小鼠Kars重組蛋白
貨號(hào)：

CSB-BP858769MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

小鼠Kars重組蛋白
貨號(hào)：

CSB-MP858769MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Kars
Uniprot No.：

Q99MN1
別名：

Kars1; Kars; Lysine--tRNA ligase; EC 2.7.7.-; EC 6.1.1.6; Lysyl-tRNA synthetase; LysRS
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

2-595
氨基酸序列

ATLQESEVK VDGEQKLSKN ELKRRLKAEK KLAEKEAKQK ELSEKQLNQT ASAPNHTADN GVGAEEETLD PNQYYKIRSQ AVQQLKVTGE DPYPHKFHVD ISLTQFIQEY SHLQPGDHLT DVTLKVAGRI HAKRASGGKL IFYDLRGEGV KLQVMANSRN YKSEEEFVHI NNKLRRGDII GVEGNPGKTK KGELSIIPQE ITLLSPCLHM LPHLHFGLKD KETRYRQRYL DLILNDFVRQ KFIVRSKIIT YIRSFLDELG FLEIETPMMN IIPGGAVAKP FITYHNELDM NLYMRIAPEL YHKMLVVGGI DRVYEIGRQF RNEGIDLTHN PEFTTCEFYM AYADYHDLME ITEKMLSGMV KSITGSYKIT YHPDGPEGQA YEVDFTPPFR RISMVEELEK ALGVKLPETS LFETEETRKI LDDICVAKAV ECPPPRTTAR LLDKLVGEFL EVTCISPTFI CDHPQIMSPL AKWHRSKEGL TERFELFVMK KEICNAYTEL NDPVRQRQLF EEQAKAKAAG DDEAMFIDEN FCTALEYGLP PTAGWGMGID RLTMFLTDSN NIKEVLLFPA MKPEDKKETA ATTETPESTE ASPSV
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.
基因功能參考文獻(xiàn)：
1. mitoKARS is the first described member of a group of mitochondrial proteins whose interaction with mutant SOD1 contributes to mitochondrial dysfunction in ALS PMID: 18715867
亞細(xì)胞定位：

Cytoplasm, cytosol. Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Secreted.
蛋白家族：

Class-II aminoacyl-tRNA synthetase family
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:85305

STRING: 10090.ENSMUSP00000090808

UniGene: Mm.196544