Recombinant Mouse Ly6/PLAUR domain-containing protein 6 (Lypd6)

中文名稱：

小鼠Lypd6重組蛋白
貨號：

CSB-YP806886MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Lypd6重組蛋白
貨號：

CSB-EP806886MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Lypd6重組蛋白
貨號：

CSB-EP806886MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Lypd6重組蛋白
貨號：

CSB-BP806886MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Lypd6重組蛋白
貨號：

CSB-MP806886MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Lypd6
Uniprot No.：

Q8BPP5
別名：

Lypd6Ly6/PLAUR domain-containing protein 6
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

23-171
氨基酸序列

AQSRDFTV KDIIYLHPST TPYPGGFKCF TCEKAADNYE CNRWAPDIYC PRDTRYCYTQ HTMEVTGNSI SVTKRCVPLE ECLSTGCRDS EHEGYKICTS CCEGNICNLP LPRNETDATF ATTSPINQTN GHPHCVSVIV SCLWVWLGLT L
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Enhances nicotine-induced Ca(2+) influx through nAChRs. Acts as a positive regulator of Wnt/beta-catenin signaling.
基因功能參考文獻：
1. Lypd6 appears to control Lrp6 activation specifically in membrane rafts, which is essential for downstream signaling. PMID: 23987510
2. Lypd6 seems to constitute a novel modulator of nAChRs that affects receptor function by selectively increasing Ca2+-influx through ion channels PMID: 19403274
亞細胞定位：

Secreted. Cytoplasm. Cell membrane; Lipid-anchor, GPI-anchor. Cell junction, synapse, synaptosome. Membrane raft.
組織特異性：

Highly expressed in the brain and spinal cord, as well as dorsal root and trigeminal ganglia.
數據庫鏈接：

KEGG: mmu:320343

STRING: 10090.ENSMUSP00000061578

UniGene: Mm.130607