Recombinant Mouse Leucine-rich repeat-containing protein 34 (Lrrc34)

中文名稱：

小鼠Lrrc34重組蛋白
貨號：

CSB-YP861593MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Lrrc34重組蛋白
貨號：

CSB-EP861593MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Lrrc34重組蛋白
貨號：

CSB-EP861593MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Lrrc34重組蛋白
貨號：

CSB-BP861593MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Lrrc34重組蛋白
貨號：

CSB-MP861593MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Lrrc34
Uniprot No.：

Q9DAM1
別名：

Lrrc34; Spata34Leucine-rich repeat-containing protein 34
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-415
氨基酸序列

MEKLQAQYCY LCSENIRKTN PFILNILQKL DEEIEKRPKE KFTVNIAGNN RLDSGQRITG EDFWLLSKTL RNQPCISGVD VRYNLIGDVG AFYAAKLLQK QPSITYLNLM FNDIGPEGGE LIAKALHKNK TLKYLRMTGN KIENTGGMLF AAMLQMNSSL EKLDLGDCDL GLQCVIAFST VLTQNQAIKG INLNRPILYG EQEESTVHIG HMLKENHVLV ELHMCKHGMK NYGLQQLCNA LYLNSSLRYL DVSCNKITRD GMVFLADVLK SNTTLEVLDL SFNRIETAGA KYLSETLTSH NRSLKALSVV SNKIEGEGLV ALSQSMKTNL VLSNIYIWGN KFDEDTCVAY SDLIKSGRLK PDNTDVEPYM VDEHIYLSEV SNGLKRHYYW APTYGETYMP SSSAGFALVP VGEHL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro.
基因功能參考文獻：
1. LRRC34 is a novel nucleolar protein that is predominantly expressed in pluripotent stem cells. PMID: 24991885
2. Overexpression of Spata34 in COS7 cells inhibited the transcriptional activity of AP-1, p53 and p21 which suggested that Spata34 protein may act as a transcriptional repressor in p53 and p21 pathway PMID: 24435972
3. Lrrc34 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia. PMID: 17971504
亞細胞定位：

Nucleus. Nucleus, nucleolus. Cytoplasm.
組織特異性：

Expressed in testis where it specifically localizes to germ cells (at protein level). Not detected in other tissues tested (at protein level). Expressed in pluripotent embryonic stem cells and multipotent adult germline stem cells.
數據庫鏈接：

KEGG: mmu:71827

STRING: 10090.ENSMUSP00000029252

UniGene: Mm.45373