Recombinant Mouse Kelch-like protein 1 (Klhl1)

中文名稱：

小鼠Klhl1重組蛋白
貨號：

CSB-YP862363MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Klhl1重組蛋白
貨號：

CSB-EP862363MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Klhl1重組蛋白
貨號：

CSB-EP862363MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Klhl1重組蛋白
貨號：

CSB-BP862363MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Klhl1重組蛋白
貨號：

CSB-MP862363MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Klhl1
Uniprot No.：

Q9JI74
別名：

Klhl1Kelch-like protein 1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-751
氨基酸序列

MSGSGRKDFD VKHILRLRWK LFSHPSPASS SPAGGSCLQQ DSGGGSFEHW GPSQSRLLKN QEKGSVSAFW KKPSSSSSSS SSSSSSASSS PFNPLNGTLL PVATRLQQGA PGQGTQQPAR TLFYVESLEE EVVTGMDFSG PEDKGLALKE LQAEPASSIQ ATGEGCGHRL TSTNHSLTPQ SDLDSSSSEE FYQAVHHAEQ SFRKMENYLK QQQLCDVILI VGNRKIPAHR LVLSSVSDYF AAMFTSDVCE AKQEEIKMEG IDPNALWDLV QFAYTGCLEL KEDTIENLLA AACLLQLPQV VEVCCHFLMK LLHPSNCLGI RAFADAQGCI ELMKVAHSYT MENIMEVIRN QEFLLLPAEE LHKLLASDDV NVPDEETIFH ALMMWVKYDM QRRCSDLSML LAFIRLPLLP PQILADLENH ALFKNDLECQ KLILEAMKYH LLPERRTLMQ SPRTKPRKST VGTLYAVGGM DNNKGATTIE KYDLRTNLWI QAGMMNGRRL QFGVAVIDDK LFVIGGRDGL KTLNTVECYN PKTKTWTVLP PMSTHRHGLG VTVLEGPIYA VGGHDGWSYL NTVERWDPQS QQWTYVASMS IARSTVGVAA LNGKLYSVGG RDGSSCLSSM EYYDPHTNKW SMCAPMCKRR GGVGVATCDG FLYAVGGHDA PASNHCSRLL DYVERYDPKT DTWTMVAPLS MPRDAVGVCL LGDRLYAVGG YDGQTYLNTM ESYDPQTNEW TQMASLNIGR AGACVVVIKQ P
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May play a role in organizing the actin cytoskeleton of the brain cells.
基因功能參考文獻：
1. KLHL1 requires actin-polymerization to increase T-Type Calcium Channel alpha(1H) currents PMID: 19806008
2. KLHL1 interacts with Cav3.2 and modulates T-type calcium currents by increasing current deactivation kinetics and current density and calcium influx. PMID: 20147652
3. MRP2/KLHL1 has a role, through its interaction with actin, in the process elongation of oligodendrocytes PMID: 17324934
4. KLHL! was widely distributed throughout the mouse brain. In the mouse testis, Sca8 transcript colocalized with Klhl1 mRNA in the spermatogenic cells. PMID: 18708037
5. Dlk1 is required to prevent premature expression of Dat in meso-diencephalic dopamine neuronal precursors as part of the multifaceted process of neuronal differentiation driven by Nurr1 and Pitx3. PMID: 19515692
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亞細胞定位：

Cytoplasm, cytoskeleton.
組織特異性：

Highly expressed in brain.
數據庫鏈接：

KEGG: mmu:93688

STRING: 10090.ENSMUSP00000022666

UniGene: Mm.308735