Recombinant Mouse Hyaluronan and proteoglycan link protein 2 (Hapln2)

中文名稱：

小鼠Hapln2重組蛋白
貨號：

CSB-YP010131MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Hapln2重組蛋白
貨號：

CSB-EP010131MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Hapln2重組蛋白
貨號：

CSB-EP010131MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Hapln2重組蛋白
貨號：

CSB-BP010131MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Hapln2重組蛋白
貨號：

CSB-MP010131MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Hapln2
Uniprot No.：

Q9ESM3
別名：

Hapln2; Bral1; Hyaluronan and proteoglycan link protein 2; Brain link protein 1
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

28-341
氨基酸序列

NPA PHPGPHYLLP PIHEVIHSRR GATATLPCVL GTSPPSYKVR WSKVEPGELR ETLILITNGL HARDYGLLGG RASLRRGHRL DASLIIKNVR LEDEGRYRCE LINGIEDESV ALTLRLEGVV FPYQPSRGRY QFNYFEAKRA CEEQDGRLAT YGQLYQAWTE GLDWCNAGWL LEGSVRYPVL TARAPCGGHG RPGIRSYGPR DRSRDRYDAF CFTSALAGQV FFVPGRLTLS EAHAACRRRG AVVAKVGHLY AAWKFSGLDQ CDGGWLADGS VRFPITTPRP RCGGLPDPGV RSFGFPRPQQ ASYGTYCYAE K
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid.
基因功能參考文獻：
1. These findings provide an understanding of the mechanisms underlying the accumulation of cations due to diffusion barriers around the nodes during saltatory conduction, emphasizing the importance of the Bral1-based extramilieu for neuronal conductivity. PMID: 20181608
2. colocalizing with the versican V2 isoform at the nodes of Ranvier in developing and adult mouse central nervous systems. PMID: 11817897
亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

HAPLN family
組織特異性：

Brain. Predominantly expressed by neurons. Colocalizes with versican V2 in developing and adult cerebellar white matter and at the nodes of Ranvier.
數據庫鏈接：

KEGG: mmu:73940

STRING: 10090.ENSMUSP00000005014

UniGene: Mm.294467