Recombinant Mouse Heat shock protein beta-7 (Hspb7)

中文名稱：

小鼠Hspb7重組蛋白
貨號：

CSB-YP010838MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Hspb7重組蛋白
貨號：

CSB-EP010838MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Hspb7重組蛋白
貨號：

CSB-EP010838MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Hspb7重組蛋白
貨號：

CSB-BP010838MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Hspb7重組蛋白
貨號：

CSB-MP010838MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Hspb7
Uniprot No.：

P35385
別名：

Hspb7; Cvhsp; Hsp25-2Heat shock protein beta-7; HspB7; Cardiovascular heat shock protein; cvHsp; Heat shock protein 25 kDa 2; Protein p19/6.8
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區(qū)域：

1-169
氨基酸序列

MSHRTSSAFR AERSFRSSSS SSSSSSSSAS RALPAQDPPM EKALSMFSDD FGSFMLPHSE PLAFPARPGG QGNIKTLGDA YEFTVDMRDF SPEDIIVTTF NNHIEVRAEK LAADGTVMNT FAHKCQLPED VDPTSVTSAL REDGSLTIRA RRHPHTEHVQ QTFRTEIKI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

基因功能參考文獻：
1. The authors found that deleting HSPB7 resulted in uncontrolled elongation of actin filaments and the formation of atypical actin filament bundles in cardiomyocytes. PMID: 29078393
2. our findings characterize HSPB7 as an intercalated disc protein and suggest it has an essential role in maintaining intercalated disc integrity and conduction function in the adult heart. PMID: 28827800
3. these data indicate that MEF2 and AP-1 confer antagonistic regulation of Hspb7 gene expression in skeletal muscle, with implications for autophagy and muscle atrophy. PMID: 27632998
4. this paper shows that skeletal-muscle-specific ablation of the HspB7 causes postnatal death owing to a respiration defect, with progressive myopathy phenotypes in the diaphragm PMID: 26929074
5. HSPB7 is a potential early biomarker after MI and serves as an independent risk factor of ACS in patients with acute chest pain. PMID: 22785082
6. These results imply that HspB2 and HspB7 might be up-regulated by ethanol during the short-term differentiation of neural stem cells. PMID: 20871982
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亞細胞定位：

Cytoplasm. Nucleus. Nucleus, Cajal body.
蛋白家族：

Small heat shock protein (HSP20) family
組織特異性：

Found in both cardiac and slow skeletal (soleus) muscle.
數(shù)據(jù)庫鏈接：

KEGG: mmu:29818

STRING: 10090.ENSMUSP00000099544

UniGene: Mm.46181