Recombinant Mouse Germ cell-less protein-like 1 (Gmcl1)

中文名稱：

小鼠Gmcl1重組蛋白
貨號：

CSB-YP849708MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Gmcl1重組蛋白
貨號：

CSB-EP849708MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Gmcl1重組蛋白
貨號：

CSB-EP849708MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Gmcl1重組蛋白
貨號：

CSB-BP849708MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Gmcl1重組蛋白
貨號：

CSB-MP849708MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Gmcl1
Uniprot No.：

Q920G9
別名：

Gmcl1; Gcl; Gcl1Germ cell-less protein-like 1; mGcl-1; DP-interacting protein; DIP
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-524
氨基酸序列

MGALSSRVLR PAGRTEQPEP TPGAGGAARR SDAGEDAGHS FCYCPGGRKR KRSSGTFCYC HPDSETDDDE DEGDEQQRLL NTPRRKKLKS TSKYIYQTLF LNGENSDIKI CALGEEWSLH KIYLCQSGYF SSMFSGSWKE SSMNIIELEI PDQNIDIEAL QVAFGSLYRD DVLIKPSRVV AILAAACMLQ LDGLIQQCGE TMKETISVRT VCGYYTSAGT YGLDSVKKKC LEWLLNNLMT HQSVELFKEL SINVMKQLIG SSNLFVMQVE MDVYTALKKW MFLQLVPSWN GSLKQLLTET DVWFSKWKKD FEGTTFLETE QGKPFAPVFR HLRLQYIISD LASARIIEQD SLVPSEWLAA VYKQQWLAML RAEQDSEVGP QEINKEELEG NSMRCGRKLA KDGEYCWRWT GFNFGFDLLV TYTNRYIIFK RNTLNQPCSG SVSLQPRRSI AFRLRLASFD SSGKLICSRA TGYQILTLEK DQEQVVMNLD SRLLIFPLYI CCNFLYISPE KRTESNRHPE NPGH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport.
基因功能參考文獻：
1. Gmcl1 interacts with the DP component of the E2F transcription factor. PMID: 9878064
2. the mgcl-1 gene product appears to be essential for appropriate nuclear-lamina organization, which in turn is essential for normal sperm morphogenesis and chromatin remodeling. PMID: 12556490
3. mGCL-1 is a factor modulating MDM2-p53 axis by enhanced degradation of MDM2 PMID: 12927808
亞細胞定位：

Nucleus matrix.
組織特異性：

Ubiquitously expressed at low levels throughout development and in adult tissues.
數據庫鏈接：

KEGG: mmu:23885

STRING: 10090.ENSMUSP00000001185

UniGene: Mm.321452