Recombinant Mouse GTP-binding protein GEM (Gem)

中文名稱：

小鼠Gem重組蛋白
貨號：

CSB-YP009362MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Gem重組蛋白
貨號：

CSB-EP009362MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Gem重組蛋白
貨號：

CSB-EP009362MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Gem重組蛋白
貨號：

CSB-BP009362MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Gem重組蛋白
貨號：

CSB-MP009362MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Gem
Uniprot No.：

P55041
別名：

Gem; KirGTP-binding protein GEM; GTP-binding mitogen-induced T-cell protein; RAS-like protein KIR
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-295
氨基酸序列

MTLNNVTMRQ GTVGMQPQQR WSIPADARHL MVQKDPHPCN LRNRHSTAPE EHCRRSWSSD STDSVISSES GNTYYRVVLI GEQGVGKSTL ANIFAGVHDS MDSDCEVLGE DTYERTLVVD GESATIILLD MWENKGENEW LHDHCMQVGD AYLIVYSITD RASFEKASEL RIQLRRARQT EDIPIILVGN KSDLVRCREV SVSEGRACAV VFDCKFIETS AAVQHNVKEL FEGIVRQVRL RRDSKEKNER RLAYQKRRES IPRKARRFWG KIVAKNNKNM AFKLKSKSCH DLSVL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
基因功能參考文獻：
1. Rad, Gem and Rem all reduce depolarization-dependent Ca2+ entry in developing myotubes. PMID: 24476902
2. These results suggest that Gem plays an important role in normal beta-cell function by regulation of calcium signalling. PMID: 22761801
3. Mechanism of the inhibition of calcium channel activity by Gem. PMID: 15615719
4. docking of the RGK protein to the nucleotide-kinase domain of the Cavbeta subunit is reminiscent of the binding of GMP to guanylate kinase PMID: 17303572
5. Results identify specific nuclear localization signals (NLS) in Kir/Gem that are both required and sufficient for nuclear transport. PMID: 17605761
6. protein expression regulation; calcium channel expression PMID: 11395774
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亞細胞定位：

Cell membrane; Peripheral membrane protein; Cytoplasmic side.
蛋白家族：

Small GTPase superfamily, RGK family
數據庫鏈接：

KEGG: mmu:14579

STRING: 10090.ENSMUSP00000029868

UniGene: Mm.247486