Recombinant Mouse GPI-linked NAD (P) (+)--arginine ADP-ribosyltransferase 1 (Art1)

中文名稱：

Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
貨號：

CSB-YP733724MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
貨號：

CSB-EP733724MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
貨號：

CSB-EP733724MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
貨號：

CSB-BP733724MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(Art1)
貨號：

CSB-MP733724MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Art1
Uniprot No.：

Q60935
別名：

Art1; Art2; GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1; EC 2.4.2.31; ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono(ADP-ribosyl)transferase 1; YAC-1; CD antigen CD296
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

23-290
氨基酸序列

QSYSISQL DIFSQETPLD MAPASFDDQY AGCLADMTAA LPDLNHSEFQ ANKVYADGWA QANNQWQERR AWGSVWGSLP PSPPGFRDEH GVALLAYTAN SPLHKEFNAA VREAGRSRAH YLHHFSFKTL HFLLTEALQL LRSHRSRGCQ QVYRGVHGLR FRPAGPGATV RLGGFASASL KNVAAQQFGE DTFFGIWTCL GAPIRGYSFF PEEEEVLIPP FETFQVINTS RPTQGPARIY LRALGKRSTY NCEYIKEKKC RSGPCWLGSS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Has ADP-ribosyltransferase activity toward GLP1R.
基因功能參考文獻：
1. The results demonstrated that ART1 gene silencing inhibited the growth of the spleen transplanted tumor and its ability to spread to the liver via metastasis. PMID: 28138708
2. data suggest that ART1 promoted the expression of HIF-1alpha via the Akt pathway in tumor cells. PMID: 26847718
3. the apoptosis rate in the ART1-cDNA CT26 cells treated with PARP-1 inhibitor 5-aminoisoquinoline (5-AIQ) and cisplatin increased, when compared with the ART1-cDNA CT26 cells treated with cisplatin only or the untreated ART1-cDNA CT26 cells. PMID: 24676941
4. ART1 knockdown reduced survival rate correlated with reduced levels of phos-Akt(Thr308) and phos-IkappaBalpha and reduced NF-kappaB p65 nuclear translocation. PMID: 24335275
5. Successive amino- or carboxyl-terminal truncations of ART1, an arginine-specific transferase, identified regions that regulated transferase and NAD glycohydrolase activities. PMID: 12721285
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亞細胞定位：

Sarcoplasmic reticulum membrane; Lipid-anchor, GPI-anchor.
蛋白家族：

Arg-specific ADP-ribosyltransferase family
組織特異性：

Abundantly expressed in cardiac and skeletal muscle. Low levels also found in lung.
數據庫鏈接：

KEGG: mmu:11870

STRING: 10090.ENSMUSP00000033300

UniGene: Mm.261071