Recombinant Mouse FYVE, RhoGEF and PH domain-containing protein 4 (Fgd4)

中文名稱：

小鼠Fgd4重組蛋白
貨號(hào)：

CSB-YP835608MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

小鼠Fgd4重組蛋白
貨號(hào)：

CSB-EP835608MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

小鼠Fgd4重組蛋白
貨號(hào)：

CSB-EP835608MO-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Fgd4重組蛋白
貨號(hào)：

CSB-BP835608MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

小鼠Fgd4重組蛋白
貨號(hào)：

CSB-MP835608MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Fgd4
Uniprot No.：

Q91ZT5
別名：

Fgd4FYVE; RhoGEF and PH domain-containing protein 4; Actin filament-binding protein frabin; FGD1-related F-actin-binding protein
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-766
氨基酸序列

MEESNPAPTS CTSKGKHSKV SDLISHFEGG SVLSSYIDLQ KDSTMNLNIP QTLGQPGLTS SPPRKFLPQH SPQKQENDPD QTQGQHGCLA NGVVAAQNQM ECEDEKETTL SPEMAIQTAA ASPDTHVLNG ERNETITDSA SSIANSHDEN ASDSSCRTPG TDLGLPSKEG EPGMDAELQE RENGVNTMGL DTLDQHHEVK ETNEQKLHKI ATELLLTERA YVSRLDLLDQ VFYCKLLEEA NRGSFPAEMV NKIFSNISSI NAFHSKFLLP ELEKRMQEWE TTPRIGDILQ KLAPFLKMYG EYVKGFDNAV ELVKTMTERV PQFKSVTEEI QKQKICGSLT LQHHMLEPIQ RIPRYEMLLK DYLKKLSPDS PDWNDAKKSL EIISTAASHS NSAIRKMENL KKLLEIYEML GEEEDIVNPS NELIKEGQIL KLAARNTSAQ ERYLFLFNNM LLYCVPRFSL VGSKFTVRTR VGIDGMKIVE THNEEYPHTF QISGKERTLE LQASSEQDKE EWIKALQESI DAFHQRHETF RNAIAKENDI PLEVSTAELG KRAPRWIRDN EVTMCMKCKE SFNALTRRRH HCRACGHVVC WKCSDYKAQL EYDGGRLNKV CKDCYQIISG FTDSEEKKRR GILEIESAEV SGNSEVCSFL QYMEKSKPWQ KIWCVIPKQD PLVLYMYGAP QDVRAQATIP LLGYVVDDMP KSADLPHSFK LTQSKSVHSF AADNEELKQK WLKIILLAVT GETPDGPSEH LATLNNLPGP KKKSEC
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates MAPK8. Plays a role in regulating the actin cytoskeleton and cell shape. Promotes the formation of lamellipodia.
基因功能參考文獻(xiàn)：
1. This study demonistrated that the disease-initiating event in CMT4H is loss of a Schwann cell-specific cellular function of Frabin/Fgd4. PMID: 23171661
亞細(xì)胞定位：

Cytoplasm, cytoskeleton. Cell projection, filopodium.
組織特異性：

Detected in thymus, lung, heart, skeletal muscle, small intestine, liver, kidney, spleen and testis. Expressed in all parts of the brain and in the spinal cord at embryonic, postnatal, and adult stages. Levels of expression are lower in postnatal and adul
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:224014

STRING: 10090.ENSMUSP00000125174

UniGene: Mm.256131