Recombinant Mouse DNA replication complex GINS protein SLD5 (Gins4)

中文名稱：

小鼠Gins4重組蛋白
貨號：

CSB-YP858762MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Gins4重組蛋白
貨號：

CSB-EP858762MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Gins4重組蛋白
貨號：

CSB-EP858762MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Gins4重組蛋白
貨號：

CSB-BP858762MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Gins4重組蛋白
貨號：

CSB-MP858762MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Gins4
Uniprot No.：

Q99LZ3
別名：

Gins4; Sld5; DNA replication complex GINS protein SLD5; GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5; N-terminally processed]
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-223
氨基酸序列

MTEVLDLHGQ DSDGGSEEMV LTPAELIEKL EQAWMNEKFA PELLESKAEI VECVMEQLEH MEENLRRAKK GDLKVSIHRM EMERIRYVLS SYLRCRLMKI EKFFPHILEK EKVRSEGEPS SLSPEEFVFA KEYMDHTETH FKNVALKHMP PNLQKVDLLR AVPKPDLDSY VFLRVKERQE NILVEPEADE QRDYVIDLEV GSQHLIRYKT IAPLVASGAV QLI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA.
基因功能參考文獻：
1. Attenuation of SLD5 expression results in marked DNA damage in both normal cells and cancer cells, suggesting that it protects against DNA damage. PMID: 25334017
2. Requirement of SLD5 for early embryogenesis. PMID: 24244394
3. These data suggest that PSF1 and SLD5 may cooperate in the proliferation of immature cell populations. PMID: 16338220
亞細胞定位：

Nucleus. Chromosome. Cytoplasm.
蛋白家族：

GINS4/SLD5 family
組織特異性：

Highly abundant in testis. Weakly expressed in thymus and bone marrow.
數據庫鏈接：

KEGG: mmu:109145

STRING: 10090.ENSMUSP00000033950

UniGene: Mm.27945