Recombinant Mouse DNA-directed RNA polymerase I subunit RPA34 (Cd3eap)

中文名稱：

Recombinant Mouse DNA-directed RNA polymerase I subunit RPA34(Cd3eap)
貨號：

CSB-YP758837MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse DNA-directed RNA polymerase I subunit RPA34(Cd3eap)
貨號：

CSB-EP758837MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse DNA-directed RNA polymerase I subunit RPA34(Cd3eap)
貨號：

CSB-EP758837MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse DNA-directed RNA polymerase I subunit RPA34(Cd3eap)
貨號：

CSB-BP758837MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse DNA-directed RNA polymerase I subunit RPA34(Cd3eap)
貨號：

CSB-MP758837MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cd3eap
Uniprot No.：

Q76KJ5
別名：

Cd3eap; Ase1; Paf49; DNA-directed RNA polymerase I subunit RPA34; A34.5; Anti-sense to ERCC-1 protein; ASE-1; CD3-epsilon-associated protein; CD3E-associated protein; RNA polymerase I-associated factor PAF49
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-399
氨基酸序列

MAGTQACSAT RFSCPPHFTE MSPDSEPSRF SLEALTGPDT ELWLIQAPAD FAPQCLNGRR VPLSGSKTVK GKLDGKKHRY RVFTSSPQAR EATLLASSSE AGGRLTCAPA PSGSLRIMEG PQEYLLSRVP LQLIPTSLPP QIPAGLRPRF SAFGGSPPVT GPGSASALRS PTSGKRKSTR KGTDASSDTQ EAVNRHGAME VKTALGNLGV SVKKRKRYFM QEEMEAKTME PVAELPVPSA TSSKKRKKSK GTETSQVEHT EPVAQTEPPE GTFLFPTKKR KRQKEADGTE EVDGIVADSQ PQVIVEAQEE TILLSPTKKR RKEKRQNLGM EAEMGPPGVL MVTEHSEHGL QAEVALVSPK KTKKKKGKRV GETEAALPDD FEPQGALAPS KKKERGARL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Involved in UBTF-activated transcription, presumably at a step following PIC formation.
基因功能參考文獻：
1. yeast A34.5/A49 and mammalian PAF49/PAF53 heterodimeric complexes interact through species-specific sequence elements that appear to assume similar structural motifs. PMID: 22849406
2. These results strongly suggest that RNA polymerase I (Pol I)-associated factor PAF49/ASE-1 plays an important role in rRNA transcription. PMID: 15226435
3. Serial deletion analysis revealed that amino acids 199-338 were necessary for the nucleolar localization of PAF49. PMID: 18329376
亞細胞定位：

Nucleus, nucleolus. Note=Accumulates in the nucleolus of exponentially growing cells.
蛋白家族：

Eukaryotic RPA34 RNA polymerase subunit family
數據庫鏈接：

KEGG: mmu:70333

STRING: 10090.ENSMUSP00000044653

UniGene: Mm.171370