Recombinant Mouse Cytohesin-interacting protein (Cytip)

中文名稱：

Recombinant Mouse Cytohesin-interacting protein(Cytip)
貨號：

CSB-YP849652MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Cytohesin-interacting protein(Cytip)
貨號：

CSB-EP849652MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Cytohesin-interacting protein(Cytip)
貨號：

CSB-EP849652MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Cytohesin-interacting protein(Cytip)
貨號：

CSB-BP849652MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Cytohesin-interacting protein(Cytip)
貨號：

CSB-MP849652MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cytip
Uniprot No.：

Q91VY6
別名：

Cytip; PscdbpCytohesin-interacting protein; Cytohesin-binding protein HE; Cbp HE; Pleckstrin homology Sec7 and coiled-coil domains-binding protein
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-359
氨基酸序列

MSLQRFLQRQ GSNGNLEYCA DSAYGSYSVL TGQLTMEDNR RIQVLADTVA TLPRGRKQLA LARSSSLGDF SWSQRKVVTV EKQDNGTFGF EIQTYRLQNQ NICSSEVCTM ICKVQEDSPA HCAGLQVGDI FANVNGVSTE GFTHKQVVDL IRSSGNLLTI ETLNGTMIHR RAELEAKLQT LKQTLKKKWV ELRSLHLQEQ RLLHGDTANS PNLENMDLDE SSLFGNLLGP SPALLDRHRL SSESSCKSWL SSLTVDSEDG YRSSMSEDSI RGAFSRQTST DDECFHSKDG DEILRNASSR RNRSISVTSS GSFSPLWESN YSSVFGTLPR KSRRGSVRKQ ILKFIPGLHR AVEEEESRF
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
基因功能參考文獻(xiàn)：
1. Data suggest a suppressive function for Cytip in mouse dendritic cells in limiting immune responses. PMID: 22488362
2. expression in vivo is differentially modulated by type 1 cytokines during lymphocyte maturation PMID: 16809763
3. These data suggest that Cybr is not absolutely required for hematopoietic cell development or function, but stem cells lacking Cybr are at a developmental disadvantage compared to wild-type cells. PMID: 16914744
4. Cybr represses the expression of T-bet and IFN-gamma via an inhibition of p38 in T-cells and consequently reduces host resistance to bacterial infection in mice. PMID: 19744714
亞細(xì)胞定位：

Cytoplasm. Early endosome.
數(shù)據(jù)庫鏈接：

KEGG: mmu:227929

STRING: 10090.ENSMUSP00000028175

UniGene: Mm.273905