Recombinant Mouse Cellular nucleic acid-binding protein (Cnbp)

中文名稱：

Recombinant Mouse Cellular nucleic acid-binding protein(Cnbp)
貨號(hào)：

CSB-YP005637MO
說明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

Recombinant Mouse Cellular nucleic acid-binding protein(Cnbp)
貨號(hào)：

CSB-EP005637MO
說明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

Recombinant Mouse Cellular nucleic acid-binding protein(Cnbp)
貨號(hào)：

CSB-EP005637MO-B
說明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Cellular nucleic acid-binding protein(Cnbp)
貨號(hào)：

CSB-BP005637MO
說明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Cellular nucleic acid-binding protein(Cnbp)
貨號(hào)：

CSB-MP005637MO
說明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cnbp
Uniprot No.：

P53996
別名：

Cnbp; Cnbp1; Znf9Cellular nucleic acid-binding protein; CNBP; Zinc finger protein 9
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

2-178
氨基酸序列

SSNECFKCG RSGHWARECP TGGGRGRGMR SRGRGGFTSD RGFQFVSSSL PDICYRCGES GHLAKDCDLQ EDEACYNCGR GGHIAKDCKE PKREREQCCY NCGKPGHLAR DCDHADEQKC YSCGEFGHIQ KDCTKVKCYR CGETGHVAIN CSKTSEVNCY RCGESGHLAR ECTIEATA
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression. Has a role as transactivator of the Myc promoter. Binds single-stranded RNA in a sequence-specific manner. Binds G-rich elements in target mRNA coding sequences. Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs.
基因功能參考文獻(xiàn)：
1. our study suggests that CNBP could maintain testicular development by inhibiting the Wnt/beta-catenin pathway, particularly by influencing Sertoli cells. PMID: 29743260
2. A G-rich motif in the lncRNA Braveheart interacts with Cnbp to specify the cardiovascular lineage. PMID: 27618485
3. data support a role for CNBP as a critical transcription factor and a key regulator of the prolonged expression of sustained cytokine IL-6 during persistent LPS stimulation or Gram-negative bacterial infection PMID: 28168305
4. CNBP up-regulates tbx2b and smarca5, and down-regulates wnt5b gene expression. PMID: 23667590
5. expression of APP(Swe) in murine tissue induces a decrease in CNBP expression. PMID: 20621159
6. CNBP targets Myc in rostral head formation, is essential for forebrain induction and specification. PMID: 12588852
顯示更多

收起更多
亞細(xì)胞定位：

Nucleus. Cytoplasm. Endoplasmic reticulum.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:12785

STRING: 10090.ENSMUSP00000032138

UniGene: Mm.290251