Recombinant Mouse Cell migration-inducing and hyaluronan-binding protein (Cemip), partial

中文名稱：

Recombinant Mouse Cell migration-inducing and hyaluronan-binding protein(Cemip),partial
貨號：

CSB-YP807356MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Cell migration-inducing and hyaluronan-binding protein(Cemip),partial
貨號：

CSB-EP807356MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Cell migration-inducing and hyaluronan-binding protein(Cemip),partial
貨號：

CSB-EP807356MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Cell migration-inducing and hyaluronan-binding protein(Cemip),partial
貨號：

CSB-BP807356MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Cell migration-inducing and hyaluronan-binding protein(Cemip),partial
貨號：

CSB-MP807356MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cemip
Uniprot No.：

Q8BI06
別名：

Cemip; Kiaa1199Cell migration-inducing and hyaluronan-binding protein; EC 3.2.1.35; Protein 12H19.01.T7
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
基因功能參考文獻：
1. KIAA1199 is overexpressed in pancreatic intraepithelial neoplasia. PMID: 27922049
2. This work identifies KIAA1199 as a novel regulator of MEK/ERK-induced Schwann cell dedifferentiation and contributes to a better understanding of the molecular control of Schwann cell dedifferentiation. PMID: 28699206
3. Results indicate that HYaluronan Binding Protein Involved in hyaluronan Depolymerization (Hybid) plays a key role in memory function in the brain. PMID: 28189611
亞細胞定位：

Nucleus. Cytoplasm. Endoplasmic reticulum. Cell membrane. Membrane, clathrin-coated pit. Secreted.
蛋白家族：

TMEM2 family
組織特異性：

Expressed in Deiters' cells and various supporting cells in the organ of Corti including inner phalangeal, border, inner and outer pillar cells (at protein level). Weakly expressed in brain and testis. In ear, it is specifically expressed in inner ear. Ex
數據庫鏈接：

KEGG: mmu:80982

STRING: 10090.ENSMUSP00000063277

UniGene: Mm.160389