Recombinant Mouse Calcium-binding and coiled-coil domain-containing protein 1 (Calcoco1)

中文名稱：

Recombinant Mouse Calcium-binding and coiled-coil domain-containing protein 1(Calcoco1)
貨號：

CSB-YP807025MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Calcium-binding and coiled-coil domain-containing protein 1(Calcoco1)
貨號：

CSB-EP807025MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Calcium-binding and coiled-coil domain-containing protein 1(Calcoco1)
貨號：

CSB-EP807025MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Calcium-binding and coiled-coil domain-containing protein 1(Calcoco1)
貨號：

CSB-BP807025MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Calcium-binding and coiled-coil domain-containing protein 1(Calcoco1)
貨號：

CSB-MP807025MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Calcoco1
Uniprot No.：

Q8CGU1
別名：

Calcoco1; CocoA; Kiaa1536Calcium-binding and coiled-coil domain-containing protein 1; Coiled-coil coactivator protein
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-691
氨基酸序列

MEESSLSRAP SRGGVNFLNV ARTYIPNTKV ECHYTLPPGT MPSASDWIGI FKVEAACVRD YHTFVWSSVP ESTTDGSPTH ASVQFQASYL PKPGAQLYQF RYVNRQGRVC GQSPPFQFRE PRPMDELVTL EEADGGSDIL LVVPKATVLQ NQLDESQQER NDLMQLKLQL EDQVTELRSR VQELEAALAT ARQEHSELTE QYKGLSRSHG ELSEERDILS QQQGDHVARI LELEDDIQTM SDKVLMKEVE LDRVRDTVKA LTREQEKLLR QLKEFQADKE QSEAELQTVR EENCCLNTEL EEAKSRQEEQ GAQVQRLKDK LAHMKDTLGQ AQQKVAELEP LKEQLRGVQE LAASSQQKAA LLGEELASAA GARDRTIAEL HRSRLEVAEV NGRLAELSLH MKEEKCQWSK ERTGLLQSME AEKDKILKLS AEILRLEKTV QEERTQSHVF KTELAREKDS SLVQLSESKR ELTELRSALR VLQKEKEQLQ TEKQELLEYM RKLEARLEKV ADEKWTEDAA TEDEEATAGL SCPASLTDSE DESPEDMRLP SYGLCESGNT SSSPPGPREP SSLVVINQPA PIAPQFSGPG EASSSDSEAE DEKSVLMAAV QSGGEEASLL LPELGSAFYD VASAFTVSSL SEASPGVPAN PPWKECPICK ERFPAESDKD ALEGHMDGHF FFSTQDPFTF E
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions. In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells.
基因功能參考文獻：
1. CoCoA and CCAR1 appear to relay the GATA1 signal to MED1, and multiple modes of the GATA1-MED1 axis may help to fine-tune GATA1 function during GATA1-mediated homeostasis events. PMID: 24245781
亞細胞定位：

Cytoplasm. Nucleus. Note=Shuttles between nucleus and cytoplasm.
蛋白家族：

CALCOCO family
組織特異性：

Expressed in all tissues examined except spleen, with high levels of expression in the heart and kidney.
數據庫鏈接：

KEGG: mmu:67488

STRING: 10090.ENSMUSP00000023818

UniGene: Mm.71682