Recombinant Mouse CCR4-NOT transcription complex subunit 6-like (Cnot6l)

中文名稱：

Recombinant Mouse CCR4-NOT transcription complex subunit 6-like(Cnot6l)
貨號：

CSB-YP837726MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse CCR4-NOT transcription complex subunit 6-like(Cnot6l)
貨號：

CSB-EP837726MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse CCR4-NOT transcription complex subunit 6-like(Cnot6l)
貨號：

CSB-EP837726MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse CCR4-NOT transcription complex subunit 6-like(Cnot6l)
貨號：

CSB-BP837726MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse CCR4-NOT transcription complex subunit 6-like(Cnot6l)
貨號：

CSB-MP837726MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cnot6l
Uniprot No.：

Q8VEG6
別名：

Cnot6lCCR4-NOT transcription complex subunit 6-like; EC 3.1.13.4
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-555
氨基酸序列

MRLIGMPKEK YDPPDPRRIY TIMSAEEVAN GKKSHWAELE ISGRVRSLST SLWSLTHLTA LHLNDNNLAR IPPDIAKLHN LVYLDLSSNK LRSLPAELGN MVSLRELLLN DNYLRVLPYE LGRLFQLQTL GLTGNPLSQD IMSLYQDPDG TRKLLNFMLD NLAVHPEQLP PRPWITLKER DQILPSASFT VMCYNVLCDK YATRQLYGYC PSWALNWEYR KKGIMEEIVN WDADIISLQE VETEQYFTLF LPALKDRGYD GFFSPKSRAK IMSEQERKHV DGCAIFFKTE KFTLVQKHTV EFNQVAMANS DGSEAMLNRV MTKDNIGVAV VLEVHKELFG TGMKPIHAAD KQLLIVANAH MHWDPEYSDV KLIQTMMFVS EVKNILEKAS SRPGSPTADP NSIPLVLCAD LNSLPDSGVV EYLSNGGVAD NHKDFKELRY NECLMNFSCS GKNGSSEGRI THGFQLKSAY ENNLMPYTNY TFDFKGVIDY IFYSKTHMNV LGVLGPLDPQ WLVENNITGC PHPHIPSDHF SLLTQLELHP PLLPLVNGVH LPNRR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. Involved in deadenylation-dependent degradation of CDKN1B mRNA. Its mRNA deadenylase activity can be inhibited by TOB1. Mediates cell proliferation and cell survival and prevents cellular senescence.
基因功能參考文獻：
1. CCR4b may be involved in various cellular events that include cell proliferation. PMID: 17452450
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

CCR4/nocturin family
數據庫鏈接：

KEGG: mmu:231464

STRING: 10090.ENSMUSP00000108629

UniGene: Mm.28374