Recombinant Mouse C-C chemokine receptor type 10 (Ccr10), partial

中文名稱：

Recombinant Mouse C-C chemokine receptor type 10(Ccr10),partial
貨號：

CSB-YP878098MO1
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse C-C chemokine receptor type 10(Ccr10),partial
貨號：

CSB-EP878098MO1
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse C-C chemokine receptor type 10(Ccr10),partial
貨號：

CSB-EP878098MO1-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse C-C chemokine receptor type 10(Ccr10),partial
貨號：

CSB-BP878098MO1
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse C-C chemokine receptor type 10(Ccr10),partial
貨號：

CSB-MP878098MO1
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ccr10
Uniprot No.：

Q9JL21
別名：

Ccr10; Cmkbr9; Gpr2; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR-10; Chemokine C-C receptor 9; G-protein coupled receptor 2
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level.
基因功能參考文獻：
1. this study shows that losartan and dexamethasone may suppress inflammatory responses in IgA nephropathy by inhibiting CCR10 expression in Th22 cells PMID: 27930971
2. controls innate and memory immune responses in the skin PMID: 24767879
3. Our in vivo analysis demonstrated that uniform expression of Ccr10 on MSCs and alteration of Ccl27 level in the skin enhance extravasation of stem cells from circulation and facilitate their migration within cutaneous tissue PMID: 23321329
4. These findings provide definite evidence that CCR10 is important in skin intraepithelial Vgamma3(+) T lymphocyte development PMID: 20937851
5. Blocking CCR4 and CCR10 simultaneously, or their ligands, should be beneficial in the treatment of T-cell-mediated skin diseases. PMID: 18095942
6. CCR10 is critical for efficient localization and accumulation of immunoglobulin A antibody-secreting cells to the lactating mammary gland. PMID: 18941222
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亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family
組織特異性：

Expressed at high levels in small intestine, colon, lymph nodes, Peyer patches and at lower levels in thymus, lung and spleen.
數據庫鏈接：

KEGG: mmu:12777

STRING: 10090.ENSMUSP00000062588

UniGene: Mm.8021