Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (Baiap2l1)

中文名稱：

Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(Baiap2l1)
貨號：

CSB-YP872045MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(Baiap2l1)
貨號：

CSB-EP872045MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(Baiap2l1)
貨號：

CSB-EP872045MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(Baiap2l1)
貨號：

CSB-BP872045MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(Baiap2l1)
貨號：

CSB-MP872045MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Baiap2l1
Uniprot No.：

Q9DBJ3
別名：

Baiap2l1; IrtksBrain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; BAI1-associated protein 2-like protein 1; Insulin receptor tyrosine kinase substrate
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-514
氨基酸序列

MSRGPEEVNR LTENTYRNVM EQFNPGLRNL INLGKNYEKA VNAMILAGKA YYDGVAKIGE IATGSPVSTE LGHVLIEISS THKKLNETLD ENFKKFHKDI IHELEKKTEL DVKYMNATLK RYQAEHRNKL DSLEKSQAEL KKIRRKSQGG RNALKYEHKE IEYVETVTSR QSEIQKFIAD GCKEALLEEK RRFCFLVDKH CSFASHIHYY HMQSAELLNS KLPRWQETCC DATKVPEKIM NMIEEIKTPI STPVSGTPQP SPMIERSKMI GKDYDTLSKY SPKMPPAPSV KAYTSPLIDM FNNPATAAQS SEKTNNSTAN TGEDPSLQRS VSVATGLNMM KKQKVKTIFP HTAGNNKTLL SFAQGDVLTL LIPEEKDGWL YGEHDTTKAR GWFPSSYTKL LEENEAMSVP TPSPAPVRSI STVDLTEKSS VVIPPPDYLE CLSMGATSDK KAGAPKVPSA STFRAPVSRP DATSTSPSDA NGTAKPPFLS GENPFATVKL RPTVTNDRSA PIIR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.
基因功能參考文獻：
1. double knockout of IRSp53 and its closest family member, IRTKS, resulted in exacerbated placental abnormalities, particularly in spongiotrophoblast differentiation and development, giving rise to complete embryonic lethality. PMID: 28067313
2. Rho family GTPases use the I-BAR proteins, IRSp53 (also known as BAIAP2), IRTKS and Pinkbar, as a central mechanism to modulate cell morphology. PMID: 27278019
3. The IRTKS, as an adaptor of the insulin receptor (IR), modulates IR-IRS1-PI3K-AKT signaling via regulating the phosphorylation of IR. PMID: 23896986
4. IRTKS functions as a negative modulator of excessive inflammation in viral infections. PMID: 26348439
亞細胞定位：

Cytoplasm, cytoskeleton.
組織特異性：

Detected in bladder, liver, testes, heart, lung, spleen, brain and skeletal muscle (at protein level).
數據庫鏈接：

KEGG: mmu:66898

STRING: 10090.ENSMUSP00000053129

UniGene: Mm.18814