Recombinant Mouse Bestrophin-2 (Best2), partial

中文名稱：

Recombinant Mouse Bestrophin-2(Best2),partial
貨號：

CSB-YP805252MO1
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Bestrophin-2(Best2),partial
貨號：

CSB-EP805252MO1
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Bestrophin-2(Best2),partial
貨號：

CSB-EP805252MO1-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Bestrophin-2(Best2),partial
貨號：

CSB-BP805252MO1
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Bestrophin-2(Best2),partial
貨號：

CSB-MP805252MO1
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Best2
Uniprot No.：

Q8BGM5
別名：

Best2; Vmd2l1; Bestrophin-2; Vitelliform macular dystrophy 2-like protein 1
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
基因功能參考文獻：
1. Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon PMID: 20407206
2. Best2 plays a role in the generation of IOP by regulating formation of aqueous humor, and inhibition of Best2 function represents an attractive new avenue for regulating IOP in individuals with glaucoma. PMID: 18385076
3. Determined HCO3(-)/Cl(-) transport via Best2 and the effect of disease causing mutations. PMID: 18400985
4. suggest a role of bestrophin 1 and 2 for Ca(2+) dependent Cl(-) secretion in mouse airways PMID: 18652850
5. Asp-rich domain has two defined binding sites and D301A and D304A mutations may impact the binding of the metal ions PMID: 19262692
6. Results suggest that bestrophin 2 plays a critical role during differentiation and growth of axons and cilia. PMID: 19480000
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亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Bestrophin family
組織特異性：

Mainly confined to the retinal pigment epithelium and colon.
數據庫鏈接：

KEGG: mmu:212989

STRING: 10090.ENSMUSP00000053408

UniGene: Mm.215154