Recombinant Mouse Basic leucine zipper transcriptional factor ATF-like 2 (Batf2)

中文名稱：

Recombinant Mouse Basic leucine zipper transcriptional factor ATF-like 2(Batf2)
貨號：

CSB-YP844435MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Basic leucine zipper transcriptional factor ATF-like 2(Batf2)
貨號：

CSB-EP844435MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Basic leucine zipper transcriptional factor ATF-like 2(Batf2)
貨號：

CSB-EP844435MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Basic leucine zipper transcriptional factor ATF-like 2(Batf2)
貨號：

CSB-BP844435MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Basic leucine zipper transcriptional factor ATF-like 2(Batf2)
貨號：

CSB-MP844435MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Batf2
Uniprot No.：

Q8R1H8
別名：

Batf2Basic leucine zipper transcriptional factor ATF-like 2; B-ATF-2
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-277
氨基酸序列

MQLCGSSELL TETDLGESQK QLKKKQKNRV AAQRSRQKHT SKADALHQQH ESLEKQNHAL RKEIQALQTE LAGWGRTLHL HERLCRVDCD PCPVLLPSGC PIQAKQPSGQ PAPLGYNGCQ EQLGLFQTPG SSPRAQHLSP GPCSHESPGL LPSLLPSLAF DPLMVRTPLA QLSPSPVLSA SSPSGSSLLG SFSKLDPLIP SPQDQLAPPQ PLRQEQPTSG RLASSDSPAA LGPECSQNRE HLPALPGSST HWQKSSVAPS PQALMAFPLL SSAKVHF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Selectively suppresses CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CCN1 and inhibits CCN1-induced anchorage-independent growth and invasion in several cancer types. Possibly acts by interfering with AP-1 binding to CCN1 promoter. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.
基因功能參考文獻：
1. Gain- and loss-of-function studies uncovered a role for Batf2 in myeloid differentiation in both murine and human systems. We thus demonstrate that chronic infection can deplete HSPCs and identify BATF2 as a mediator of infection-induced HSPC terminal differentiation PMID: 27926863
2. controls Th17-mediated immunopathology by suppressing IL-23 production during Trypanosoma cruzi infection PMID: 28356392
3. Batf2 has a central role in macrophage activation by regulating inflammatory responses during lipopolysaccharides stimulation and mycobacterial infection PMID: 26376615
4. these results underline the role of Batf2/Irf1 in inducing inflammatory responses in M. tuberculosis infection. PMID: 25957166
亞細胞定位：

Nucleus.
蛋白家族：

BZIP family
數據庫鏈接：

KEGG: mmu:74481

STRING: 10090.ENSMUSP00000045744

UniGene: Mm.159219