Recombinant Mouse Augurin (Ecrg4)

中文名稱：

小鼠Ecrg4重組蛋白
貨號：

CSB-YP859978MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Ecrg4重組蛋白
貨號：

CSB-EP859978MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Ecrg4重組蛋白
貨號：

CSB-EP859978MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Ecrg4重組蛋白
貨號：

CSB-BP859978MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Ecrg4重組蛋白
貨號：

CSB-MP859978MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ecrg4
Uniprot No.：

Q99LS0
別名：

Ecrg4Augurin; Esophageal cancer-related gene 4 protein homolog
種屬：

Mus musculus (Mouse)
蛋白長度：

Cytoplasmic domain
表達區域：

71-132
氨基酸序列

QLWDRTRPEV QQWYQQFLYM GFDEAKFEDD VNYWLNRNRN GHDYYGDYYQ RHYDEDAAIG PH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.
基因功能參考文獻：
1. a wound termination factor during wound resolution after cutaneous injury PMID: 22899245
2. proteolytic cleavage by furin is a posttranslational requirement for proaugurin to suppress cell proliferation PMID: 21436262
3. identified esophageal cancer-related gene 4 (Ecrg4) as a senescence inducer with implications for the senescence-like state of postmitotic cells in the aging brain. PMID: 20404145
4. ECRG4 level in differentiated chondrocytes is decreased during hypertrophic maturation PMID: 19735703
亞細胞定位：

Secreted. Cytoplasm. Apical cell membrane.
蛋白家族：

Augurin family
組織特異性：

Expressed in the intermediate lobe of pituitary, glomerular layer of adrenal cortex, choroid plexus and atrioventricular node of the heart. Expressed in the brain with high expression in the choroid plexus and the epithelial lining of the central canal an
數據庫鏈接：

KEGG: mmu:78896

UniGene: Mm.50109