Recombinant Mouse Actin-binding protein anillin (Anln), partial

中文名稱：

Recombinant Mouse Actin-binding protein anillin(Anln) ,partial
貨號：

CSB-YP810375MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Actin-binding protein anillin(Anln) ,partial
貨號：

CSB-EP810375MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Actin-binding protein anillin(Anln) ,partial
貨號：

CSB-EP810375MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Actin-binding protein anillin(Anln) ,partial
貨號：

CSB-BP810375MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Actin-binding protein anillin(Anln) ,partial
貨號：

CSB-MP810375MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Anln
Uniprot No.：

Q8K298
別名：

AnlnAnillin
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase and anaphase of mitosis. May play a significant role in podocyte cell migration.
基因功能參考文獻：
1. Loss of ANLN expression is associated with tumorigenesis in liver. PMID: 29429824
2. Knockdown of ANLN in liver cells blocks cytokinesis and inhibits development of liver tumors. PMID: 29274368
3. data suggest that anillin is an essential intracellular component that maintains the integrity of asymmetric division in mouse oocytes. PMID: 27508507
4. Anillin is excluded from the cortex of first polar body, enriched in the cytokinetic ring that severs the polar body from the oocyte. In meiosis II, anillin is enriched in a cortical stripe coincident with and overlying the meiotic spindle midzone. PMID: 25818309
5. Results show that targeting of mDia2 to the cleavage furrow requires not only its binding to RhoA but also its diaphanous-inhibitory domain, and identify anillin as a novel mDia2 interaction partner. PMID: 20660154
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亞細胞定位：

Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell projection, bleb.
數據庫鏈接：

KEGG: mmu:68743

STRING: 10090.ENSMUSP00000045873

UniGene: Mm.282751