Recombinant Human cytomegalovirus Uncharacterized protein UL21A (UL21A)

中文名稱：

Recombinant Human cytomegalovirus Uncharacterized protein UL21A(UL21A)
貨號(hào)：

CSB-YP752126HWV
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human cytomegalovirus Uncharacterized protein UL21A(UL21A)
貨號(hào)：

CSB-EP752126HWV
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human cytomegalovirus Uncharacterized protein UL21A(UL21A)
貨號(hào)：

CSB-EP752126HWV-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human cytomegalovirus Uncharacterized protein UL21A(UL21A)
貨號(hào)：

CSB-BP752126HWV
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human cytomegalovirus Uncharacterized protein UL21A(UL21A)
貨號(hào)：

CSB-MP752126HWV
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

UL21A
Uniprot No.：

Q7M6R1
別名：

UL21A; Uncharacterized protein UL21A
種屬：

Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-123
氨基酸序列

MGGSPVPQLT TVTQGLMPSV RMDFRARRPL RRLAFYAPRA RRRLFQNHIH PEQRRVLVGE GDEEMLPDLP MEIDIVIDRP PQQPLPNPLV LLLDDVPPHV PGFAPYRVPR PHPMIPEEHW DQF
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Required for efficient viral DNA synthesis and the late accumulation of viral IE transcripts.
基因功能參考文獻(xiàn)：
1. Cyclin A2-binding function of pUL21a contributes to the maintenance of a cell cycle state conducive for the completion of the human cytomegalovirus (HCMV) replication cycle. PMID: 25393019
2. Human Cytomegalovirus UL21a but not UL97 can disrupt APC/C function, leading to the accumulation of substrates and that UL21a is necessary and sufficient to induce the degradation of APC1, in addition to the previously reported APC4 and APC5. PMID: 25903336
3. study reveals the HCMV protein pUL21a as a novel anaphase-promoting complex (APC) regulator and uncovers a unique viral mechanism to subvert APC activity PMID: 22792066
4. pUL21a does not promote the functionality of human cytomegalovirus virions; rather, its de novo synthesis facilitates viral DNA synthesis, which is necessary for the late accumulation of IE transcripts and establishment of a productive infection. PMID: 21047969
亞細(xì)胞定位：

Host cytoplasm.
蛋白家族：

HHV-5 UL21A protein family
數(shù)據(jù)庫鏈接：

KEGG: vg:3077448