Recombinant Human adenovirus C serotype 2 Maturation protein (PIVA2)

中文名稱：

Recombinant Human adenovirus C serotype 2 Maturation protein(PIVA2)
貨號：

CSB-YP355998HIK
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human adenovirus C serotype 2 Maturation protein(PIVA2)
貨號：

CSB-EP355998HIK
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human adenovirus C serotype 2 Maturation protein(PIVA2)
貨號：

CSB-EP355998HIK-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human adenovirus C serotype 2 Maturation protein(PIVA2)
貨號：

CSB-BP355998HIK
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human adenovirus C serotype 2 Maturation protein(PIVA2)
貨號：

CSB-MP355998HIK
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

IVa2
Uniprot No.：

P03272
別名：

IVa2; Packaging protein 1; Packaging protein IVa2
種屬：

Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
蛋白長度：

full length protein
表達區域：

1-449
氨基酸序列

METRGRRPAA LQHQQDQPQA HPGQRAARSA PLHRDPDYAD EDPAPVERHD PGPSGRAPTT AVQRKPPQPA KRGDMLDRDA VEHVTELWDR LELLGQTLKS MPTADGLKPL KNFASLQELL SLGGERLLAH LVRENMQVRD MLNEVAPLLR DDGSCSSLNY QLQPVIGVIY GPTGCGKSQL LRNLLSSQLI SPTPETVFFI APQVDMIPPS ELKAWEMQIC EGNYAPGPDG TIIPQSGTLR PRFVKMAYDD LILEHNYDVS DPRNIFAQAA ARGPIAIIMD ECMENLGGHK GVSKFFHAFP SKLHDKFPKC TGYTVLVVLH NMNPRRDMAG NIANLKIQSK MHLISPRMHP SQLNRFVNTY TKGLPLAISL LLKDIFRHHA QRSCYDWIIY NTTPQHEALQ WCYLHPRDGL MPMYLNIQSH LYHVLEKIHR TLNDRDRWSR AYRARKTPK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the packaging machinery which encapsidates the viral DNA into preformed capsids and transcriptional activator of the viral major late promoter (MLP). Binds, along with packaging proteins 2 and 3, to the specific packaging sequence on the left end of viral genomic DNA and displays ATPase activity thereby providing the power stroke of the packaging machinery. The activity of packaging protein IVa2 is stimulated by protein 33K which acts as a terminase. May be the protein that pumps DNA into the capsid powered by ATP hydrolysis. Specifically binds to the 5'-CG-3' nucleotides of the repeats making up the packaging sequence. Component of the DEF-A and DEF-B transcription factors that bind downstream elements of the major late promoter (MLP), and stimulate transcription from the MLP after initiation of viral DNA replication. DEF-A is a heterodimer packaging proteins 1 and 2 and DEF-B is a homodimer of packaging protein 1.
基因功能參考文獻：
1. IVa2, 33K and DBP form a complex at a unique vertex on viral capsids and cooperate in genome packaging. PMID: 23388198
2. The authors conclude that the major role of IVa2 is in viral DNA packaging. PMID: 21450831
亞細胞定位：

Virion. Host nucleus, host nucleoplasm. Host nucleus, host nucleolus.
蛋白家族：

Adenoviridae packaging protein 1 family
數據庫鏈接：

KEGG: vg:5739974