Recombinant Human Zinc finger protein 671 (ZNF671)

中文名稱：

人ZNF671重組蛋白
貨號：

CSB-YP026937HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人ZNF671重組蛋白
貨號：

CSB-EP026937HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人ZNF671重組蛋白
貨號：

CSB-EP026937HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人ZNF671重組蛋白
貨號：

CSB-BP026937HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人ZNF671重組蛋白
貨號：

CSB-MP026937HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ZNF671
Uniprot No.：

Q8TAW3
別名：

ZNF671; Zinc finger protein 671
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-534
氨基酸序列

MLSPVSRDAS DALQGRKCLR PRSRRLPLPA AVRAHGPMAE LTDSARGCVV FEDVFVYFSR EEWELLDDAQ RLLYHDVMLE NFALLASLGI AFSRSRAVMK LERGEEPWVY DQVDMTSATE REAQRGLRPG CWHGVEDEEV SSEQSIFVAG VSEVRTLMAE LESHPCDICG PILKDTLHLA KYHGGKARQK PYLCGACGKQ FWFSTDFDQH QNQPNGGKLF PRKEGRDSVK SCRVHVPEKT LTCGKGRRDF SATSGLLQHQ ASLSSMKPHK STKLVSGFLM GQRYHRCGEC GKAFTRKDTL ARHQRIHTGE RPYECNECGK FFSQSYDLFK HQTVHTGERP YECSECGKFF RQISGLIEHR RVHTGERLYQ CGKCGKFFSS KSNLIRHQEV HTGARPYVCS ECGKEFSRKH TLVLHQRTHT GERPYECSEC GKAFSQSSHL NVHWRIHSSD YECSRCGKAF SCISKLIQHQ KVHSGEKPYE CSKCGKAFTQ RPNLIRHWKV HTGERPYVCS ECGREFIRKQ TLVLHQRVHA GEKL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be involved in transcriptional regulation.
基因功能參考文獻：
1. Data show that mRNA and protein expression of ZNF671 are down-regulated in nasopharyngeal cancer (NPC) tissues and cell lines. Its downregulation promotes NPC cell proliferation and tumorigenicity by facilitating cell cycle progression. These results suggest that ZNF671 is a potential tumor suppressor which epigenetically silenced by promoter methylation in NPC. PMID: 29052525
2. In particular, methylation levels of ITGA4, RERG, and ZNF671 could distinguish Nasopharyngeal carcinoma (NPC) patients from non-cancer nasopharyngeal epithelium (NNE) subjects. We identified the DNA methylation rates of previously unidentified NPC candidate genes. PMID: 28716111
3. Data show that ZNF671, an epigenetically silenced tumor suppressor, represents a potential predictor for urothelial carcinoma (UC) relapse and non-invasive biomarker that could assist in UC clinical decision-making. PMID: 26320192
亞細胞定位：

Nucleus.
蛋白家族：

Krueppel C2H2-type zinc-finger protein family
數據庫鏈接：

HGNC: 26279

KEGG: hsa:79891

STRING: 9606.ENSP00000321848

UniGene: Hs.180402