Recombinant Human Zinc finger HIT domain-containing protein 1 (ZNHIT1)

中文名稱：

人ZNHIT1重組蛋白
貨號：

CSB-YP027109HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人ZNHIT1重組蛋白
貨號：

CSB-EP027109HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人ZNHIT1重組蛋白
貨號：

CSB-EP027109HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人ZNHIT1重組蛋白
貨號：

CSB-BP027109HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人ZNHIT1重組蛋白
貨號：

CSB-MP027109HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ZNHIT1
Uniprot No.：

O43257
別名：

ZNHIT1; CGBP1; ZNFN4A1; Zinc finger HIT domain-containing protein 1; Cyclin-G1-binding protein 1; Zinc finger protein subfamily 4A member 1; p18 Hamlet
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達區域：

1-154
氨基酸序列

MVEKKTSVRS QDPGQRRVLD RAARQRRINR QLEALENDNF QDDPHAGLPQ LGKRLPQFDD DADTGKKKKK TRGDHFKLRF RKNFQALLEE QNLSVAEGPN YLTACAGPPS RPQRPFCAVC GFPSPYTCVS CGARYCTVRC LGTHQETRCL KWTV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity.
基因功能參考文獻：
1. p18(Hamlet) is a new cell-fate regulator that links the p38 MAPK and p53 pathways and contributes to the establishment of p53-regulated stress responses. PMID: 17380123
2. Study reports that p18(Hamlet) can also mediate the cell cycle arrest induced in response to gamma-irradiation, by participating in the p53-dependent upregulation of the cell cycle inhibitor p21(Cip1) (CDKN1A). PMID: 17700068
亞細胞定位：

Nucleus.
蛋白家族：

ZNHIT1 family
組織特異性：

Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.
數據庫鏈接：

HGNC: 21688

KEGG: hsa:10467

STRING: 9606.ENSP00000304593

UniGene: Hs.211079