Recombinant Human Uncharacterized protein CXorf67 (CXorf67)

中文名稱：

Recombinant Human Uncharacterized protein CXorf67(CXorf67)
貨號：

CSB-YP768227HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Uncharacterized protein CXorf67(CXorf67)
貨號：

CSB-EP768227HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Uncharacterized protein CXorf67(CXorf67)
貨號：

CSB-EP768227HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Uncharacterized protein CXorf67(CXorf67)
貨號：

CSB-BP768227HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Uncharacterized protein CXorf67(CXorf67)
貨號：

CSB-MP768227HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

CXorf67
Uniprot No.：

Q86X51
別名：

EZHIP; CXorf67EZH inhibitory protein
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-503
氨基酸序列

MATQSDMEKE QKHQQDEGQG GLNNETALAS GDACGTGNQD PAASVTTVSS QASPSGGAAL SSSTAGSSAA AATSAAIFIT DEASGLPIIA AVLTERHSDR QDCRSPHEVF GCVVPEGGSQ AAVGPQKATG HADEHLAQTK SPGNSRRRKQ PCRNQAAPAQ KPPGRRLFPE PLPPSSPGFR PSSYPCSGAS TSSQATQPGP ALLSHASEAR PATRSRITLV ASALRRRASG PGPVIRGCTA QPGPAFPHRA THLDPARLSP ESAPGPARRG RASVPGPARR GCDSAPGPAR RGRDSAPVSA PRGRDSAPGS ARRGRDSAPG PALRVRTARS DAGHRSTSTT PGTGLRSRST QQRSALLSRR SLSGSADENP SCGTGSERLA FQSRSGSPDP EVPSRASPPV WHAVRMRASS PSPPGRFFLP IPQQWDESSS SSYASNSSSP SRSPGLSPSS PSPEFLGLRS ISTPSPESLR YALMPEFYAL SPVPPEEQAE IESTAHPATP PEP
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Inhibits PRC2/EED-EZH1 and PRC2/EED-EZH2 complex function by inhibiting EZH1/EZH2 methyltransferase activity, thereby causing down-regulation of histone H3 trimethylation on 'Lys-27' (H3K27me3). Probably inhibits methyltransferase activity by limiting the stimulatory effect of cofactors such as AEBP2 and JARID2. Inhibits H3K27me3 deposition during spermatogenesis and oogenesis.
基因功能參考文獻(xiàn)：
1. The chimeric MBTD1-CXorf67 fusion identifies yet another cytogenetically distinct subgroup of low-grade Endometrial stromal sarcomas and offers the opportunity to shed light on the functions of two poorly characterized genes. PMID: 23959973
2. Meta-analysis of gene-disease association. (HuGE Navigator) PMID: 20564319
亞細(xì)胞定位：

Nucleus. Cytoplasm.
組織特異性：

In testis, detected in male germ cells inside the seminiferous tubules, especially in spermatogonia and round spermatids (at protein level). In the ovary, expressed in primordial follicles and oocytes but not the external follicle cells (at protein level)
數(shù)據(jù)庫鏈接：

HGNC: 33738

KEGG: hsa:340602

STRING: 9606.ENSP00000342680

UniGene: Hs.97053