Recombinant Human UNC5C-like protein (UNC5CL), partial

中文名稱：

人UNC5CL重組蛋白
貨號：

CSB-YP818233HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人UNC5CL重組蛋白
貨號：

CSB-EP818233HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人UNC5CL重組蛋白
貨號：

CSB-EP818233HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人UNC5CL重組蛋白
貨號：

CSB-BP818233HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人UNC5CL重組蛋白
貨號：

CSB-MP818233HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

UNC5CL
Uniprot No.：

Q8IV45
別名：

UNC5CL; ZUDUNC5C-like protein; Protein unc-5 homolog C-like; ZU5 and death domain-containing protein
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets.
基因功能參考文獻：
1. rs2294693 near UNC5CL was significantly associated with Gastric non-cardia cancer risk (p=2.50x10(-8)), with OR (95% CI) of 1.18 (1.12 to 1.26), but there was only a nominal association for cardia cancer (p=1.47x10(-2). PMID: 26129866
2. The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade. PMID: 22158417
3. ZUD is an inhibitor of NF-kappaB activation and may provide an alternative regulatory mechanism for NF-kappaB-mediated transcription PMID: 14769797
亞細胞定位：

Membrane; Single-pass type III membrane protein. Cytoplasm.
蛋白家族：

Unc-5 family
組織特異性：

Expressed in pancreas, liver and kidney.
數據庫鏈接：

HGNC: 21203

OMIM: 617464

KEGG: hsa:222643

STRING: 9606.ENSP00000244565

UniGene: Hs.158357