Recombinant Human Tubulin polyglutamylase TTLL11 (TTLL11)

中文名稱：

人TTLL11重組蛋白
貨號(hào)：

CSB-YP844084HU
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

人TTLL11重組蛋白
貨號(hào)：

CSB-EP844084HU
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

人TTLL11重組蛋白
貨號(hào)：

CSB-EP844084HU-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人TTLL11重組蛋白
貨號(hào)：

CSB-BP844084HU
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

人TTLL11重組蛋白
貨號(hào)：

CSB-MP844084HU
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

TTLL11
Uniprot No.：

Q8NHH1
別名：

C9orf20; TTL11_HUMAN; Ttll11; Tubulin polyglutamylase TTLL11; Tubulin--tyrosine ligase-like protein 11
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-538
氨基酸序列

MAAAASVTGR VTWAASPMRS LGLGRRLSLP GPRLDAVTAA VNPSLSDHGN GLGRGTRGSG CSGGSLVADW GGGAAAAAAV ALALAPALST MRRGSSESEL AARWEAEAVA AAKAAAKAEA EATAETVAEQ VRVDAGAAGE PECKAGEEQP KVLAPAPAQP SAAEEGNTQV LQRPPPTLPP SKPKPVQGLC PHGKPRDKGR SCKRSSGHGS GENGSQRPVT VDSSKARTSL DALKISIRQL KWKEFPFGRR LPCDIYWHGV SFHDNDIFSG QVNKFPGMTE MVRKITLSRA VRTMQNLFPE EYNFYPRSWI LPDEFQLFVA QVQMVKDDDP SWKPTFIVKP DGGCQGDGIY LIKDPSDIRL AGTLQSRPAV VQEYICKPLL IDKLKFDIRL YVLLKSLDPL EIYIAKDGLS RFCTEPYQEP TPKNLHRIFM HLTNYSLNIH SGNFIHSDSA STGSKRTFSS ILCRLSSKGV DIKKVWSDII SVVIKTVIAL TPELKVFYQS DIPTGRPGPT CFQVTIASSQ PAFPALTGLK RALWLRVG
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Preferentially mediates ATP-dependent polyglutamate long side-chain elongation over the initiation step of the polyglutamylation reaction. Preferentially modifies the alpha-tubulin tail over a beta-tail. Required for CCSAP localization to both spindle and cilia microtubules. Promotes tubulin polyglutamylation which stimulates spastin/SPAST-mediated microtubule severing, thereby regulating microtubule functions.
亞細(xì)胞定位：

Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton.
蛋白家族：

Tubulin--tyrosine ligase family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 18113

KEGG: hsa:158135

STRING: 9606.ENSP00000321346

UniGene: Hs.438937