Recombinant Human Testis-expressed protein 101(TEX101)

中文名稱：

Recombinant Human Testis-expressed protein 101(TEX101)
品名簡稱：

Recombinant Human TEX101 protein
貨號：

CSB-EP887155HU
說明書：

MSDS Datasheet
規格：

￥1536
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
生物活性：

Not Test
基因名：

TEX101
Uniprot No.：

Q9BY14
別名：

Cell surface receptor NYD-SP8;Scleroderma-associated autoantigen;Spermatogenesis-related gene protein
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

28.0 kDa
表達區域：

26-222aa
氨基酸序列

LYCQKGLSMTVEADPANMFNWTTEEVETCDKGALCQETILIIKAGTETAILATKGCIPEGEEAITIVQHSSPPGLIVTSYSNYCEDSFCNDKDSLSQFWEFSETTASTVSTTLHCPTCVALGTCFSAPSLPCPNGTTRCYQGKLEITGGGIESSVEVKGCTAMIGCRLMSGILAVGPMFVREACPHQLLTQPRKTEN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

C-terminal 6xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct. May play a role in signal transduction and promote protein tyrosine phosphorylation.
基因功能參考文獻：
1. Overexpression of TEX101 is associated with breast tumors. PMID: 25994570
2. Clinical assays for ECM1 and TEX101 have the potential to replace most of the diagnostic testicular biopsies and facilitate the prediction of outcome of sperm retrieval procedures, increasing the reliability and success of assisted reproduction techniques PMID: 24259048
3. TEX101 is a cancer-testis (CT) gene useful for detection of CML. It was expressed in 30% of CML patients, but not in healthy donors. Unlike many CT genes, overexpression of TEX101 was not shown to induce immunologic responses in these samples. PMID: 22588436
4. Combination of two proteins, SPAG11B and TEX101, can be used for differential diagnosis of azoospermia PMID: 21933954
5. Overexpression of NYD-SP8 in various nasopharyngeal carcinoma cell lines indicated its complicated functions, and that it could play an important role in nasopharyngeal carcinoma carcinogenesis. PMID: 22158499
6. NYD-SP8 has a role in regulating ECM degradation, providing a novel mechanism that modulates urokinase signalling in the suppression of cancer progression PMID: 19017363
7. The SPATA19 and TEX101 genes may be possible targets for cancer immunotherapy and novel markers for early detection of basal cell carcinoma. PMID: 19886887
8. identification & function of a novel sperm GPI-anchored membrane protein, NYD-SP8; release of NYD-SP8 during sperm-egg interaction & binding to cumulus elicits cross-talk between the gametes leading to the acrosome reaction PMID: 19153666
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亞細胞定位：

Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted. Cytoplasmic vesicle.
組織特異性：

Detected in testis and spermatogonia. Not detected in spermatocytes. Detected in blood leukocytes.
數據庫鏈接：

HGNC: 30722

OMIM: 612665

KEGG: hsa:83639

STRING: 9606.ENSP00000253435

UniGene: Hs.97978