Recombinant Human TBC1 domain family member 2A (TBC1D2), partial

中文名稱：

人TBC1D2重組蛋白
貨號：

CSB-YP861181HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人TBC1D2重組蛋白
貨號：

CSB-EP861181HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人TBC1D2重組蛋白
貨號：

CSB-EP861181HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人TBC1D2重組蛋白
貨號：

CSB-BP861181HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人TBC1D2重組蛋白
貨號：

CSB-MP861181HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

TBC1D2
Uniprot No.：

Q9BYX2
別名：

TBC1D2; PARIS1; PP8997; TBC1D2A; TBC1 domain family member 2A; Armus; Prostate antigen recognized and identified by SEREX 1; PARIS-1
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
基因功能參考文獻：
1. Armus expression induces autophagosome accumulation in keratinocytes. PMID: 23562278
2. TBC1D2/Armus, a GAP of Rab7 GTPase, is reported as a novel target of miR-17. PMID: 23285084
亞細胞定位：

Cytoplasm. Cytoplasmic vesicle. Cell junction.
組織特異性：

Expressed in a broad range of tissues, especially in kidney, liver, lung and placenta. Also expressed in keratinocytes and epithelia-containing organs. Isoform 2 is differentially expressed in prostate normal and cancer cells (at protein level).
數據庫鏈接：

HGNC: 18026

OMIM: 609871

KEGG: hsa:55357

STRING: 9606.ENSP00000364207

UniGene: Hs.371016