Recombinant Human Ras-related protein Rab-40B (RAB40B)

中文名稱：

人RAB40B重組蛋白
貨號：

CSB-YP615534HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人RAB40B重組蛋白
貨號：

CSB-EP615534HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人RAB40B重組蛋白
貨號：

CSB-EP615534HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人RAB40B重組蛋白
貨號：

CSB-BP615534HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人RAB40B重組蛋白
貨號：

CSB-MP615534HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RAB40B
Uniprot No.：

Q12829
別名：

RAB40B; SEC4L; Ras-related protein Rab-40B; SOCS box-containing protein RAR; Protein Rar
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區(qū)域：

1-278
氨基酸序列

MSALGSPVRA YDFLLKFLLV GDSDVGKGEI LASLQDGAAE SPYGHPAGID YKTTTILLDG RRVKLQLWDT SGQGRFCTIF RSYSRGAQGV ILVYDIANRW SFDGIDRWIK EIDEHAPGVP KILVGNRLHL AFKRQVPTEQ AQAYAERLGV TFFEVSPLCN FNITESFTEL ARIVLLRHGM DRLWRPSKVL SLQDLCCRAV VSCTPVHLVD KLPLPIALRS HLKSFSMANG LNARMMHGGS YSLTTSSTHK RSSLRKVKLV RPPQSPPKNC TRNSCKIS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
基因功能參考文獻：
1. This is the first study that identifies a new Rab40b-Tks5- and miR-204-dependent invadopodia transport pathway that regulates MMP2 and MMP9 secretion, and extracellular matrix remodeling during cancer progression. PMID: 27789576
2. High expression level of Rab40b was significantly correlated with gastric cancer invasion and lymph node metastasis. PMID: 25790780
3. Rab40b mediates trafficking of MMP2/9 during invadopodia formation and metastasis of breast cancer cells. PMID: 23902685
亞細胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Small GTPase superfamily, Rab family
數(shù)據(jù)庫鏈接：

HGNC: 18284

KEGG: hsa:10966

STRING: 9606.ENSP00000461785

UniGene: Hs.484068