Recombinant Human Rabankyrin-5 (ANKFY1), partial

中文名稱：

Recombinant Human Rabankyrin-5(ANKFY1),partial
貨號：

CSB-YP882184HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Rabankyrin-5(ANKFY1),partial
貨號：

CSB-EP882184HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Rabankyrin-5(ANKFY1),partial
貨號：

CSB-EP882184HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Rabankyrin-5(ANKFY1),partial
貨號：

CSB-BP882184HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Rabankyrin-5(ANKFY1),partial
貨號：

CSB-MP882184HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ANKFY1
Uniprot No.：

Q9P2R3
別名：

ANFY1_HUMAN; Ankfy1; ANKHZN; ankyrin repeat and FYVE domain containing 1; ankyrin repeat and FYVE domain containing protein 1; Ankyrin repeat and FYVE domain-containing protein 1; ankyrin repeat hooked to zinc finger motif; Ankyrin repeats hooked to a zinc finger motif; BTBD23; DKFZp686M19106; KIAA1255; Rabankyrin 5; ZFYVE14
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport.
基因功能參考文獻：
1. Rabankyrin-5 is required for internalization and trafficking of the PDGF receptor. PMID: 24102721
2. Rab5 regulates and coordinates different endocytic mechanisms through its effector Rabankyrin-5 PMID: 15328530
3. Characterization of the related mouse gene PMID: 10092534
亞細胞定位：

Cytoplasm. Endosome membrane; Peripheral membrane protein. Early endosome.
組織特異性：

High expression in whole adult brain and intermediate expression in all other tissues and specific brain regions examined, including fetal brain.
數據庫鏈接：

HGNC: 20763

OMIM: 607927

KEGG: hsa:51479

STRING: 9606.ENSP00000459775

UniGene: Hs.696087