Recombinant Human Putative cancer susceptibility gene HEPN1 protein (HEPN1)

中文名稱：

人HEPN1重組蛋白
貨號：

CSB-YP757828HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人HEPN1重組蛋白
貨號：

CSB-EP757828HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人HEPN1重組蛋白
貨號：

CSB-EP757828HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人HEPN1重組蛋白
貨號：

CSB-BP757828HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人HEPN1重組蛋白
貨號：

CSB-MP757828HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

HEPN1
Uniprot No.：

Q6WQI6
別名：

HEPN1; Putative cancer susceptibility gene HEPN1 protein
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-88
氨基酸序列

MGNWGLGIAP WVDGESELEF RRLGMQGPLE ALRRREWNTQ RASFSFSFLI ALSPHTVDYC HSYELFNRRW HGHVLATQRP SLFILMLV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. the current study suggested an underlying mechanism that miR-21 directly target HEPN1 and inhibit its expression during the carcinogenesis of HCC. HEPN1 may thus be a candidate as a therapeutic target for patients with HCC. PMID: 25687183
2. ROS increase production of an alternately spliced form of X-box binding protein 1 (XBP1s) and XBP1s increases HEPN1 expression by binding to the HEPN1 promoter PMID: 25448679
3. HEPN1 silencing increased MMP-2, MMP-9, and Bcl-2 expression, but decreased BAX, p53, and caspase-3 expression. PMID: 23548416
亞細胞定位：

Cytoplasm.
組織特異性：

Expressed in liver. Expression is either down-regulated or lost in hepatocellular carcinomas (HCC).
數據庫鏈接：

HGNC: 34400

OMIM: 611641

KEGG: hsa:641654

STRING: 9606.ENSP00000386143

UniGene: Hs.159863