Recombinant Human Probable methyltransferase C20orf7, mitochondrial (C20orf7)

中文名稱：

人NDUFAF5重組蛋白
貨號(hào)：

CSB-YP713138HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人NDUFAF5重組蛋白
貨號(hào)：

CSB-EP713138HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人NDUFAF5重組蛋白
貨號(hào)：

CSB-EP713138HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人NDUFAF5重組蛋白
貨號(hào)：

CSB-BP713138HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人NDUFAF5重組蛋白
貨號(hào)：

CSB-MP713138HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

NDUFAF5
Uniprot No.：

Q5TEU4
別名：

C20orf7; chromosome 20 open reading frame 7; CT007_HUMAN; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5; NDUFAF5; Probable methyltransferase C20orf7; mitochondrial
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

37-345
氨基酸序列

GSTS PRTLNIFDRD LKRKQKNWAA RQPEPTKFDY LKEEVGSRIA DRVYDIPRNF PLALDLGCGR GYIAQYLNKE TIGKFFQADI AENALKNSSE TEIPTVSVLA DEEFLPFKEN TFDLVVSSLS LHWVNDLPRA LEQIHYILKP DGVFIGAMFG GDTLYELRCS LQLAETEREG GFSPHISPFT AVNDLGHLLG RAGFNTLTVD TDEIQVNYPG MFELMEDLQG MGESNCAWNR KALLHRDTML AAAAVYREMY RNEDGSVPAT YQIYYMIGWK YHESQARPAE RGSATVSFGE LGKINNLMPP GKKSQ
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Arginine hydroxylase involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. Acts by mediating hydroxylation of 'Arg-111' of NDUFS7. May also have methyltransferase activity (Probable).
基因功能參考文獻(xiàn)：
1. However, similar to another family member, RdmB, it catalyzes the introduction of a hydroxyl group, in the case of NDUFAF5, into Arg-73 in the NDUFS7 subunit of human complex I PMID: 27226634
2. analysis of the combined OXPHOS complex I and IV defect, due to mutated complex I assembly factor C20ORF7 PMID: 21607760
3. A new cause of Leigh syndrome can be a defect in early complex I assembly due to C20orf7 mutations. PMID: 19542079
4. C20orf7 is crucial in the assembly of complex I and mutations in C20orf7 cause mitochondrial disease PMID: 18940309
相關(guān)疾病：

Mitochondrial complex I deficiency (MT-C1D); Leigh syndrome (LS)
亞細(xì)胞定位：

Mitochondrion inner membrane.
蛋白家族：

Methyltransferase superfamily
數(shù)據(jù)庫鏈接：

HGNC: 15899

OMIM: 252010

KEGG: hsa:79133

STRING: 9606.ENSP00000367346

UniGene: Hs.472165