Recombinant Human Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3), partial

中文名稱：

人HCN3重組蛋白
貨號：

CSB-YP868385HU1
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人HCN3重組蛋白
貨號：

CSB-EP868385HU1
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人HCN3重組蛋白
貨號：

CSB-EP868385HU1-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人HCN3重組蛋白
貨號：

CSB-BP868385HU1
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人HCN3重組蛋白
貨號：

CSB-MP868385HU1
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

HCN3
Uniprot No.：

Q9P1Z3
別名：

HCN3; KIAA1535; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions.
基因功能參考文獻：
1. Reduced HCN3 expression in aganglionic bowel suggests its potential role in Hirschsprung's disease pathophysiology. PMID: 25987789
2. KCTD3 is an accessory subunit of native HCN3 complexes PMID: 23382386
3. Genetic analysis in 48 Sudden unexpected death in epilepsy cases identified six novel and three previously reported nonsynonymous (amino acid changing) variants in HCN1 , HCN2, HCN3 and HCN4. PMID: 21615589
4. human HCN3 is not modulated by intracellular cAMP, in contrast to other HCN subtypes PMID: 16043489
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Potassium channel HCN family
組織特異性：

Detected in brain.
數據庫鏈接：

HGNC: 19183

OMIM: 609973

KEGG: hsa:57657

STRING: 9606.ENSP00000357342

UniGene: Hs.706960