Recombinant Human Poly [ADP-ribose] polymerase 15 (PARP15)

中文名稱：

人PARP15重組蛋白
貨號：

CSB-YP676066HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人PARP15重組蛋白
貨號：

CSB-EP676066HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人PARP15重組蛋白
貨號：

CSB-EP676066HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人PARP15重組蛋白
貨號：

CSB-BP676066HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人PARP15重組蛋白
貨號：

CSB-MP676066HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

PARP15
Uniprot No.：

Q460N3
別名：

PARP15; BAL3; Protein mono-ADP-ribosyltransferase PARP15; EC 2.4.2.-; ADP-ribosyltransferase diphtheria toxin-like 7; ARTD7; B-aggressive lymphoma protein 3; Poly [ADP-ribose] polymerase 15; PARP-15
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-656
氨基酸序列

MHGVAGVTSR AGRDREAGSM LPAGNRGARK ASRRSSSRSM SRDNKFSKKD CLSIRNVVAS IQTKEGLNLK LISGDVLYIW ADVIVNSVPM NLQLGGGPLS RAFLQKAGPM LQKELDDRRR ETEEKVGNIF MTSGCNLDCK AVLHAVAPYW NNGAETSWQI MANIIKKCLT TVEVLSFSSI TFPMIGTGSL QFPKAVFAKL ILSEVFEYSS STRPITSPLQ EVHFLVYTND DEGCQAFLDE FTNWSRINPN KARIPMAGDT QGVVGTVSKP CFTAYEMKIG AITFQVATGD IATEQVDVIV NSTARTFNRK SGVSRAILEG AGQAVESECA VLAAQPHRDF IITPGGCLKC KIIIHVPGGK DVRKTVTSVL EECEQRKYTS VSLPAIGTGN AGKNPITVAD NIIDAIVDFS SQHSTPSLKT VKVVIFQPEL LNIFYDSMKK RDLSASLNFQ STFSMTTCNL PEHWTDMNHQ LFCMVQLEPG QSEYNTIKDK FTRTCSSYAI EKIERIQNAF LWQSYQVKKR QMDIKNDHKN NERLLFHGTD ADSVPYVNQH GFNRSCAGKN AVSYGKGTYF AVDASYSAKD TYSKPDSNGR KHMYVVRVLT GVFTKGRAGL VTPPPKNPHN PTDLFDSVTN NTRSPKLFVV FFDNQAYPEY LITFTA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Acts as a negative regulator of transcription.
基因功能參考文獻：
1. The current study investigated the possible association between PARP15 single-nucleotide polymorphisms and the risk of acute myeloid leukemia (AML). The results from a Cox regression analysis for overall survival revealed that two polymorphisms associated with increased overall survival and the signal for rs17208928 was retained after correcting for multiple tests. rs17208928 showed a significant association with survival PMID: 27610459
亞細胞定位：

Nucleus.
數據庫鏈接：

HGNC: 26876

OMIM: 612066

KEGG: hsa:165631

STRING: 9606.ENSP00000417214

UniGene: Hs.120250