Recombinant Human Phostensin (PPP1R18)

中文名稱：

人PPP1R18重組蛋白
貨號：

CSB-YP747374HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人PPP1R18重組蛋白
貨號：

CSB-EP747374HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人PPP1R18重組蛋白
貨號：

CSB-EP747374HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人PPP1R18重組蛋白
貨號：

CSB-BP747374HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人PPP1R18重組蛋白
貨號：

CSB-MP747374HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

PPP1R18
Uniprot No.：

Q6NYC8
別名：

PPP1R18; HKMT1098; KIAA1949; Phostensin; Protein phosphatase 1 F-actin cytoskeleton-targeting subunit; Protein phosphatase 1 regulatory subunit 18
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-613
氨基酸序列

MATIPDWKLQ LLARRRQEEA SVRGREKAER ERLSQMPAWK RGLLERRRAK LGLSPGEPSP VLGTVEAGPP DPDESAVLLE AIGPVHQNRF IRQERQQQQQ QQQRSEELLA ERKPGPLEAR ERRPSPGEMR DQSPKGRESR EERLSPRETR ERRLGIGGAQ ELSLRPLEAR DWRQSPGEVG DRSSRLSEAW KWRLSPGETP ERSLRLAESR EQSPRRKEVE SRLSPGESAY QKLGLTEAHK WRPDSRESQE QSLVQLEATE WRLRSGEERQ DYSEECGRKE EWPVPGVAPK ETAELSETLT REAQGNSSAG VEAAEQRPVE DGERGMKPTE GWKWTLNSGK AREWTPRDIE AQTQKPEPPE SAEKLLESPG VEAGEGEAEK EEAGAQGRPL RALQNCCSVP SPLPPEDAGT GGLRQQEEEA VELQPPPPAP LSPPPPAPTA PQPPGDPLMS RLFYGVKAGP GVGAPRRSGH TFTVNPRRSV PPATPATPTS PATVDAAVPG AGKKRYPTAE EILVLGGYLR LSRSCLAKGS PERHHKQLKI SFSETALETT YQYPSESSVL EELGPEPEVP SAPNPPAAQP DDEEDEEELL LLQPELQGGL RTKALIVDES CRR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May target protein phosphatase 1 to F-actin cytoskeleton.; May target protein phosphatase 1 to F-actin cytoskeleton.
基因功能參考文獻：
1. phostensin is a ubiquitous protein in leukocytes, and it may play an important role in modulating the cellular functions of leukocytes. PMID: 21804078
2. our data shows that phostensin targets PP1 to F-actin cytoskeleton. PMID: 17374523
3. phostensin is an actin filament pointed end-capping protein that is capable of modulating actin dynamics. PMID: 19622346
亞細胞定位：

[Isoform 1]: Cytoplasm, cytoskeleton.; [Isoform 4]: Cytoplasm, cytoskeleton.
組織特異性：

Isoform 4 is predominantly expressed in leukocytes and spleen.
數據庫鏈接：

HGNC: 29413

OMIM: 610990

KEGG: hsa:170954

STRING: 9606.ENSP00000274853

UniGene: Hs.101150