Recombinant Human Outer dense fiber protein 2 (ODF2), partial

中文名稱：

人ODF2重組蛋白
貨號：

CSB-YP691501HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人ODF2重組蛋白
貨號：

CSB-EP691501HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人ODF2重組蛋白
貨號：

CSB-EP691501HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人ODF2重組蛋白
貨號：

CSB-BP691501HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人ODF2重組蛋白
貨號：

CSB-MP691501HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ODF2
Uniprot No.：

Q5BJF6
別名：

84 kDa outer dense fiber protein; Cancer/testis antigen 134; Cenexin 1; Cenexin; Cenexin1 variant 1; CT134; FLJ44866; KKT 4; KKT4; MGC111096; MGC9034; ODF 2; ODF 84; odf2; ODF2/1; ODF2/2; ODF84; ODFP2_HUMAN; OTTHUMP00000022274; OTTHUMP00000022275; Outer dense fiber of sperm tail 2; Outer dense fiber of sperm tails 2; Outer dense fiber of sperm tails protein 2; Outer dense fiber of sperm tails; 84 kD; Outer dense fiber protein 2; Sperm outer dense fiber major protein 2; Sperm tail structural protein; Testis specific autoantigen
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
基因功能參考文獻：
1. Cenexin controls centrosome positioning during cell migration by modulating microtubule organization and stability.Cenexin is required for spindle orientation. PMID: 26948879
2. Cby plays an important role in organization of both primary and motile cilia in collaboration with Cnx. PMID: 22911743
3. Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein. PMID: 21325031
4. Cdk5 in the centriolar appendages mediates cenexin1 localization and primary cilia formation. PMID: 20234188
5. Mouse and rat ODF2 protein homolog sequences and expression are compared. PMID: 9740324
6. We propose that hCenexin1 is a critical centrosomal component whose C-terminal extension is required for proper recruitment of Plk1 and other components crucial for normal mitosis. PMID: 16966375
7. A splice variant of hODF2 called hCenexin1, but not hODF2 itself, efficiently localizes to somatic centrosomes via a variant-specific C-terminal extension and recruits Plk1 through a Cdc2-dependent phospho-S796 motif within the extension. PMID: 19386263
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亞細胞定位：

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell projection, cilium, flagellum.
蛋白家族：

ODF2 family
組織特異性：

Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails.
數據庫鏈接：

HGNC: 8114

OMIM: 602015

KEGG: hsa:4957

STRING: 9606.ENSP00000361882

UniGene: Hs.129055