Recombinant Human Neurogenin-2 (NEUROG2)

中文名稱：

人NEUROG2重組蛋白
貨號：

CSB-YP887960HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人NEUROG2重組蛋白
貨號：

CSB-EP887960HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人NEUROG2重組蛋白
貨號：

CSB-EP887960HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人NEUROG2重組蛋白
貨號：

CSB-BP887960HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

NEUROG2
Uniprot No.：

Q9H2A3
別名：

Atoh 4; Atoh4; bHLHa8; Class A basic helix-loop-helix protein 8; Math 4A; Math4A; MGC; MGC46562; NEUROG 2; NEUROG2; Neurogenin-2; Neurogenin2; NGN 2; NGN-2; NGN2; NGN2_HUMAN; Protein atonal homolog 4
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區(qū)域：

1-272
氨基酸序列

MFVKSETLEL KEEEDVLVLL GSASPALAAL TPLSSSADEE EEEEPGASGG ARRQRGAEAG QGARGGVAAG AEGCRPARLL GLVHDCKRRP SRARAVSRGA KTAETVQRIK KTRRLKANNR ERNRMHNLNA ALDALREVLP TFPEDAKLTK IETLRFAHNY IWALTETLRL ADHCGGGGGG LPGALFSEAV LLSPGGASAA LSSSGDSPSP ASTWSCTNSP APSSSVSSNS TSPYSCTLSP ASPAGSDMDY WQPPPPDKHR YAPHLPIARD CI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
基因功能參考文獻：
1. Study shows neurogenin 2 enhances the generation of patient-specific induced neuronal cells. PMID: 25912433
2. Results show that neurogenin-1 and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media. PMID: 25403753
3. human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury PMID: 21209909
4. Novel compound heterozygous variants (Gly56Arg and Asp206Glu) were found in a 91-year normal male, suggesting that mutations in the coding region of the NEUROG2 gene play little or no role in the development of PD. PMID: 19879328
5. expression of Ngn2 during the differentiation of neuronl human embryo stem cells. PMID: 17784840
6. Rat and mouse species-dependent differences of Nurr1 and Ngn2 actions in dopamine neuron differentiation. PMID: 18242186
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亞細胞定位：

Nucleus.
數(shù)據(jù)庫鏈接：

HGNC: 13805

OMIM: 606624

KEGG: hsa:63973

STRING: 9606.ENSP00000317333

UniGene: Hs.744415