Recombinant Human Neurogenic differentiation factor 6 (NEUROD6)

中文名稱：

人NEUROD6重組蛋白
貨號：

CSB-YP846677HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人NEUROD6重組蛋白
貨號：

CSB-EP846677HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人NEUROD6重組蛋白
貨號：

CSB-EP846677HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人NEUROD6重組蛋白
貨號：

CSB-BP846677HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人NEUROD6重組蛋白
貨號：

CSB-MP846677HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

NEUROD6
Uniprot No.：

Q96NK8
別名：

Atoh 2; Atoh2; Atonal homolog 2; Atonal protein homolog 2; Atonal protein homolog2; bHLH a2; bHLHa 2; bHLHa2; Class A basic helix-loop-helix protein 2; Helix loop helix protein mATH 2; Helix loop helix protein mATH2; MATH 2; Math2; NDF 6; NDF6; NDF6_HUMAN; Neuro D6; NeuroD6; Neurogenic differentiation 6; Neurogenic differentiation factor 6; Nex 1; Nex 1m; Nex; Nex1; Nex1 m; Nex1m; Protein atonal homolog 2; Protein atonal homolog2
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-337
氨基酸序列

MLTLPFDESV VMPESQMCRK FSRECEDQKQ IKKPESFSKQ IVLRGKSIKR APGEETEKEE EEEDREEEDE NGLPRRRGLR KKKTTKLRLE RVKFRRQEAN ARERNRMHGL NDALDNLRKV VPCYSKTQKL SKIETLRLAK NYIWALSEIL RIGKRPDLLT FVQNLCKGLS QPTTNLVAGC LQLNARSFLM GQGGEAAHHT RSPYSTFYPP YHSPELTTPP GHGTLDNSKS MKPYNYCSAY ESFYESTSPE CASPQFEGPL SPPPINYNGI FSLKQEETLD YGKNYNYGMH YCAVPPRGPL GQGAMFRLPT DSHFPYDLHL RSQSLTMQDE LNAVFHN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene.
基因功能參考文獻：
1. single nucleotide polymorphisms in either the region of NEUROD6 or SNAP25 were significantly associated with Alzheimer's Disease, in APOE4+ females and APOE4+ males, respectively. PMID: 26395074
2. NeuroD6 serves as a possible biomarker for Alzheimer disease brains. PMID: 25548427
3. cloning and some features of a novel human gene, MATH2, which encodes a protein of 337 amino acid residues with a basic helix loop helix domain and exhibits 98% similarity to mouse Math2 PMID: 12357074
亞細胞定位：

Nucleus.
數據庫鏈接：

HGNC: 13804

OMIM: 611513

KEGG: hsa:63974

STRING: 9606.ENSP00000297142

UniGene: Hs.45152